Newsletter
Best Papers in General Surgery
The five that matter, every day.
Conformal thyroidectomy in low-risk PTMC patients showed advantages in perioperative management with reduced hospital stays, shorter operative times, lower complication rates, and comparable event-free survival to lobectomy. It resulted in decreased rates of vocal cord paralysis, hypoparathyroidism, and permanent hypothyroidism. This study supports the use…
CPL-01, a long-acting ropivacaine, significantly reduced postoperative pain intensity scores and opioid use in open inguinal hernia repair patients. Subjects receiving the highest CPL-01 dose showed clinically meaningful pain reduction, requiring fewer opioids and experiencing faster recovery compared to placebo and naropin groups. CPL-01 demonstrated…
Time kinetics of calcitonin normalization (CN) and biochemical persistence/recurrence (BP) after surgery for medullary thyroid carcinoma were studied in 190 patients. Early CN predicted long-term risks of recurrence, with lymph node ratio (LNR) being a significant factor. Higher primary tumor size and longer CN time…
Study on 80,070 patients undergoing hepatic resection reveals a 1.46% occurrence of postoperative delirium, with key risk factors including older age, male sex, depression, and various comorbidities. Patients with delirium had longer hospital stays, higher costs, and increased mortality rates than those without. Understanding these…
Centralization of ileo-anal pouch surgery in high-volume centers enhances patient outcomes by reducing pouch failure rates, improving reconstruction rates, and lowering readmission and complication rates. This systematic review underscores the importance of specialized care in improving outcomes for patients undergoing pouch surgery for inflammatory bowel…
Telephone questionnaire effectively diagnoses surgical site infections after abdominal surgery in low- and middle-income countries. The questionnaire discriminated between patients with and without infections, displaying high accuracy and consistent performance across different income levels. Cut-off score of ≥4 showed good sensitivity and specificity. Findings suggest…
Despite discouragement for hepatectomy in intermediate/advanced hepatocellular carcinoma, nomograms were developed and validated for predicting survival and recurrence. These nomograms, based on 10 and 6 independent variables, respectively, outperformed conventional staging systems. They accurately stratified risk and can assist clinicians in personalized surgical decisions, prognosis…
Study findings show surgery independently correlates with improved overall survival for gastrointestinal tract signet-ring cell carcinoma patients, particularly in non-metastatic cases. Surgery significantly enhances prognosis for upper gastrointestinal and left colon signet-ring cell carcinoma. A nomogram accurately predicts metastasis risk in right colon and rectum…
Improving accuracy of administrative data for perforated appendicitis classification is crucial. Two data mining algorithms, leveraging icd-10-cm codes and length of stay, showed significantly higher accuracy than those relying solely on icd-10-cm codes. With sensitivity and specificity of 0.86-0.88 and 0.95-0.97, respectively, these algorithms offer…
Genetic risk score based on 7 obesity-related genes significantly influences weight loss after bariatric surgery in patients with severe obesity. The study, conducted in Spain, revealed a substantial effect of the genetic risk score on the percentage of excess weight loss during a >60-month follow-up…
