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Best Papers in General Surgery
The five that matter, every day.
Metabolic surgery patients who achieve a healthy weight experience greater metabolic benefits compared to those with %twl >20%. This study determines the optimal weight loss target for substantial benefits post-surgery, identifying healthy weight as a more stringent goal than %twl. Patients with lower preoperative BMI…
A retrospective study of 200 patients undergoing laparoscopic robot-assisted Ivor Lewis esophagectomy revealed significant improvements in operative time, blood loss, anastomotic stricture rate, and postoperative length of stay after specific case thresholds. The procedure was shown to be safe, with enhanced outcomes and excellent oncologic…
Metabolomics analysis identified indoleacetate, 3-hydroxydecanoate, and retention index as top candidate biomarkers for early detection of pancreatic cancer in plasma samples. A logistic regression model incorporating these metabolites, along with other clinical factors, significantly improved risk prediction compared to models without these markers. Continued research…
Abdominal CT scans play a crucial role in identifying infection sources in sepsis patients with unknown origins. A retrospective cohort study found that 63.8% of patients with sepsis and fever had positive CT findings, with common sources including liver abscesses and pyelonephritis. Higher white blood…
Adrenalectomy significantly improved body weight, glucose, and blood pressure in patients with mild autonomous cortisol secretion. The study found a higher frequency of improved control in the adrenalectomy group compared to the control group. Factors like adrenalectomy, body mass index, and cortisol levels were associated…
In a study evaluating an innovative intraoperative parathyroid hormone monitoring system, 96.2% of patients undergoing parathyroidectomy for hyperparathyroidism were cured. The system showed high sensitivity (98.6%) and accuracy (98.6%) in predicting biochemical cure, with no false positives. Strong correlations with conventional devices and improvements in…
Pancreatic surgery outcomes: Snapshot study across 67 countries reveals significantly higher postoperative mortality rates in low-to-middle-HDI nations compared to high-HDI counterparts. Over two-thirds of patients experienced complications, with a 90-day mortality rate of 5.4%. Failure-to-rescue rates were notably higher in lower-HDI countries. Collaborative efforts among…
Bariatric surgery significantly reduces Apo B100 levels, improving lipid profiles and liver enzymes in high BMI individuals. Apo B100 decreased from 94.63 ± 14.35 mg/dl to 62.97 ± 19.97 mg/dl post-surgery. Reductions in cholesterol, triglycerides, LDL, VLDL, AST, and ALT were observed. Non-diabetics had greater decreases in Apo B100…
Identification of key risk factors for lymph node metastasis in early gastric cancer enables predictive modeling and personalized treatment strategies, unveiling high-risk groups based on tumor stage, histological type, and other clinicopathological markers. A retrospective analysis involving 5606 patients highlights the significance of gender, tumor…
2-stage management with laparoscopic common bile duct exploration (LCBDE) showed the shortest operation duration, lowest long-term complications, and lowest costs compared to 1-stage and preoperative endoscopic retrograde cholangiopancreatography (ERCP) strategies. All groups achieved successful stone clearance, with group 3 demonstrating superior outcomes in terms of…
