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General Surgery

Best Papers in General Surgery

The five that matter, every day.

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J Surg Oncol20 May 2024

Enhanced Disease-Free Survival in Pancreatic Cancer Patients with Neoadjuvant Chemotherapy and Vascular Resection

Neoadjuvant chemotherapy before pancreaticoduodenectomy with vascular resection led to improved disease-free survival in pancreatic cancer patients. Patients who received neoadjuvant chemotherapy had more favorable pathological outcomes, decreased vascular invasion, and completed chemotherapy more often. The neoadjuvant chemotherapy group exhibited a significant increase in disease-free survival…

Eur J Surg Oncol20 May 2024

Impact of Tumor Marker Regression Load Score on Prognosis of Gastric Cancer Patients

Novel findings suggest that the Tumor Marker Regression Load Score (TMRLS) is a significant independent prognostic factor for gastric cancer patients undergoing neoadjuvant chemotherapy and radical surgery. Patients with high TMRLS who received postoperative adjuvant chemotherapy showed better survival outcomes. The TMRLS-based nomogram demonstrated superior…

HPB (Oxford)20 May 2024

Impact of Postoperative Complications on Prognosis in Patients with Hepatocellular Carcinoma

Postoperative complications significantly impact patient outcomes in hepatocellular carcinoma. Patients with moderate/severe complications had worse recurrence-free survival compared to those with no/mild complications. Notably, low and medium alpha-feto protein-tumor burden score patients with complications had higher recurrence risks, whereas complications did not affect high score…

Intestine and Lower Gastrointestinal Tract20 May 2024

Long-term Outcomes of Primary Closure in Pilonidal Sinus Disease

Comparing two surgical techniques for pilonidal sinus disease, midline closure without skin sutures showed significant advantages over excision and primary closure. Patients in the midline closure group experienced shorter surgical procedures, hospital stays, and time to return to work. Additionally, they had lower complication rates…

J Am Coll Surg19 May 2024

Assessment of Rule-Based Guidelines for Postoperative Opioid Prescribing

Rule-based guidelines derived from in-hospital opioid consumption were compared to traditional methods for postoperative prescribing. Results show that rule-based guidelines tailored to individual patient needs outperformed fixed quantity approaches, leading to more accurate opioid prescribing. This study highlights the efficacy of personalized opioid prescribing based…

J Am Coll Surg19 May 2024

Incidence of Morbidity and Mortality in Anti-reflux and Hiatal Hernia Surgery

This study reports historic morbidity and mortality rates in anti-reflux and hiatal hernia surgery, showing a 30-day morbidity rate of 18.2% and mortality rate of 0.2%, with most complications being minor. The 31-90-day period shows decreased rates. These findings suggest that while the surgeries have…

World J Surg19 May 2024

Relaparoscopy for Severe Complications in Laparoscopic Colorectal Surgery

Relaparoscopy, guided by a standardized interdisciplinary protocol, demonstrates efficacy in managing major complications after laparoscopic colorectal surgery, leading to reduced treatment failure rates, including lower 90-day mortality and need for further surgery. Relaparoscopy, particularly in cases of anastomotic leak, correlates with shortened hospital stays, decreased…

Obes Surg19 May 2024

Effectiveness of Virtual Care in a Multidisciplinary Bariatric Program

Transition to virtual care in a bariatric program saw significant increase in virtual visits, with high patient satisfaction rates. Patient preferences varied by healthcare providers, with most patients preferring in-person visits with medical doctors. Despite the preference, virtual care offers added benefits and high satisfaction…