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Best Papers in General Surgery
The five that matter, every day.
Optimal lymphadenectomy of ≥20 lymph nodes in IPMN-derived PDAC is associated with improved overall survival. A minimum of 10 lymph nodes is needed for accurate nodal staging. Specific optimal cut-offs were identified for different types of surgeries.
Appendicoscopy had a technical success rate of 96.4% and a clinical success rate of 91.8% in diagnosing and treating acute obstructive appendicitis. The procedure time was brief at 20.9±10 minutes, with most patients experiencing pain relief within 6 hours. Hospital stays averaged 3.5±1.5 days, and…
Mucinous and non-mucinous appendiceal adenocarcinomas exhibit differences in recurrence rates and nodal positivity. Colectomy is associated with improved disease-specific survival for non-mucinous tumors at certain stages and grades, but not for mucinous tumors. This suggests that colectomy may not be necessary for mucinous appendiceal adenocarcinoma…
Mesenteric-based surgery offers insights into postoperative anastomotic recurrence in Crohn's disease. The mesenteric pole is implicated in recurrence after resection. However, the mesentery's role remains debated. This review explores mesenteric changes, its proposed role in disease progression, and the potential of mesenteric-based surgery in managing…
Procalcitonin >0.5 ng/ml at admission indicates increased risk for complicated diverticulitis, need for surgery, and mortality. It serves as a valuable tool for severity assessment and treatment decisions. The study enrolled 503 patients, revealing procalcitonin's independent association with complicated diverticulitis, surgery, and mortality, underscoring its…
The study highlights the challenges and opportunities in developing formal, professional-driven emergency medical services (Tier-2 systems) in low- and middle-income countries. These systems, which include dedicated ambulances, personnel, and equipment, can significantly reduce mortality and disability due to emergency medical and surgical conditions. Challenges include…
Large colonic adenocarcinomas are commonly right-sided, present at advanced stages, and have adverse pathologic features. Minimally invasive surgery is linked to better overall survival and shorter-term benefits compared to open surgery, offering significantly lower rates of mortality, positive margins, and shorter hospital stays for patients…
Esophageal cancer patients who underwent endoscopic submucosal dissection (ESD) for T1B tumors showed high en-bloc (100%) and R0 (82.3%) resection rates. Only 23.5% experienced tumor recurrence post-ESD, with safer outcomes in patients receiving additional therapies. Larger studies are necessary to confirm the long-term efficacy of…
This systematic review explores short- and long-term effects of omentectomy, highlighting low complication rates. Short-term complications include ileus, bowel stenosis, abscess, and sepsis (0.0%-23%). Long-term risks mainly involve donor-site hernia (up to 32%), with minimal gastrointestinal complications. However, evidence quality and follow-up duration are limited,…
BRAF mutations in colorectal cancer patients with liver metastases are linked to poorer survival outcomes. However, liver resection shows a significant 56% reduction in the risk of death for patients with BRAF-mutated colorectal liver metastases. Surgical intervention offers a clear survival benefit, with a reduced…
