A retrospective cohort study compared the long-term outcomes of T1 colorectal cancer (CRC) patients after endoscopic resection (ER) and surgery. The study found that ER can be a comparable treatment option to surgery for T1 CRC patients with deep submucosal invasion (DSI) when other high-risk factors are absent. The most important long-term prognostic factors for […]
Category: General Surgery
Outcomes of Induction Chemotherapy and Esophagectomy for Advanced Esophageal Cancer
Induction chemotherapy followed by response evaluation and esophagectomy in patients with advanced esophageal cancer showed promising results in terms of survival. A total of 238 patients were treated with taxane/platinum-based chemotherapy, with 64.7% undergoing surgical exploration. Resection was performed in 53.4% of patients, resulting in a median survival of 26.3 months and a 5-year overall […]
Liver Resection Techniques: Efficacy and Safety in Modulating Future Liver Remnant
In a systematic review and network meta-analysis of 23 studies comprising 1557 patients, lvd was found to achieve the greatest increase in flr, while alpps was most effective in preventing dropout before completion hepatectomy. Pvl tended to be associated with a longer time to completion hepatectomy, and liver failure occurred less frequently after lvd, compared […]
General Surgery Textbooks Lack Thorough Understanding of Racial Disparities in Healthcare
General surgery textbooks lack thorough understanding of racial disparities in healthcare, potentially contributing to inequities experienced by minority patients. A study analyzed 13 textbooks and found that the majority of passages discussing medical differences among racial/ethnic groups did not address systemic causes or the role of racism. Only a small percentage of passages indicated that […]
Nomogram Combined Treatment Data is More Effective than AJCC Staging System for Predicting Overall Survival in GEP-NETs
Researchers conducted a study to develop and validate a nomogram for predicting overall survival (OS) in patients with gastroenteropancreatic neuroendocrine tumors (GEP-NETs). Using data from the SEER registry, they identified key prognostic factors and compared the nomogram’s performance to the AJCC staging system. The results showed that the nomogram, which combined treatment data, had a […]
Study Finds Over Half of ESG Patients Require Opioids in the Perioperative Setting
A retrospective study on endoscopic sleeve gastroplasty (ESG) evaluated the need for peri- and postoperative opioid therapy. Of the 67 patients included, 58.2% required opioids in the perioperative setting, with a mean dose of 12.3 mg morphine milligram equivalents (MMEs). Furthermore, 17.9% of patients required home opioid prescriptions postoperatively, while more than a third reported […]
Surgeon Well-Being Impacted by Home Call: Loss of Sleep and Burnout Results
Home call for acute care surgeons was found to have detrimental effects on sleep and burnout, even without receiving calls or returning to the hospital. A study involving 224 surgeons wearing tracking devices and completing daily surveys revealed that home call without calls resulted in 3 minutes of sleep loss, while home call with calls […]
Three-Dimensional-Guided Laparoscopic Radical Resection for Left Perihilar Cholangiocarcinoma: Improved Precision and Efficiency
Utilizing three-dimensional reconstruction, clinicians performed a successful laparoscopic left hepatectomy and caudate lobectomy in a patient with left perihilar cholangiocarcinoma. The reconstruction revealed tumor invasion into the left hepatic artery and left portal vein. The procedure lasted 425 minutes with minimal blood loss. The patient’s postoperative recovery was smooth, and no recurrence was observed at […]
Pancreatectomy Induces Cancer-Promoting Neutrophil Extracellular Traps: Implications for Perioperative Management
Post-pancreatectomy, patients exhibit elevated cancer-promoting neutrophil extracellular traps (NETs), peaking on days 3 and 4, linked to changes in neutrophil biology. NET-inducing cytokines (IL-8, IL-6, G-CSF) increase postoperatively, with the robotic approach potentially reducing NETs compared to open surgery. Patients with pancreatic leaks show increased NET markers. The study suggests pancreatectomy induces cancer-promoting NET formation, […]
No Reduction in Surgical Site Infection with Dual Antibiotic Irrigation in Ventral Hernia Repair: RINSE Trial Findings
In a randomized trial for ventral hernia repair, dual antibiotic irrigation (gentamicin + clindamycin) did not significantly reduce surgical site infection (SSI) rates compared to saline irrigation. No differences were observed in secondary outcomes, suggesting that this antibiotic approach may not offer additional benefits in preventing SSIs in this context. Journal Article by Warren JA, […]