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General Surgery

Best Papers in General Surgery

The five that matter, every day.

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Hepatobiliary Surg Nutr23 Oct 2026

HCC conversion surgery matched early-stage survival

For selected patients with initially unresectable HCC who responded to conversion therapy, hepatectomy was followed by overall survival reported as comparable to direct surgery for BCLC-A disease.

Surg Endosc23 Oct 2026

OR delays track with longer MIS EGS stays

In 1,355 emergency appendectomies and cholecystectomies, longer time to the OR was associated with more inpatient admission and longer stays—without higher 30-day return visits.

J Gastrointest Cancer23 Oct 2026

Uniportal esophagectomy linked to fewer pneumonias

In nine comparative studies of minimally invasive esophagectomy for esophageal cancer, uniportal VATS was associated with less pneumonia and a shorter stay than multiportal VATS—but the evidence is not strong enough to establish a preferred approach.

Intestine and Lower Gastrointestinal Tract23 Oct 2026

Delayed rectal surgery linked to worse outcomes

In this Swedish cohort, rectal cancer surgery 28–90 days after short-course radiotherapy was associated with more recurrence, metastasis, and worse overall survival than surgery within 7 days.

Ann Surg Oncol22 Oct 2026

Pancreatic cancer: occult spread in 1 in 4

In this prospective multicenter cohort, staging laparoscopy found occult metastases in 25% of imaging-M0 patients—including 20.6% with resectable disease—potentially sparing some patients a nonbeneficial resection.

Front Surg22 Oct 2026

ICG in emergency surgery: leak evidence leads

A review finds indocyanine green fluorescence can guide anatomy and tissue perfusion in acute surgery, with the strongest clinical support for reducing anastomotic leaks.

BJS Open22 Oct 2026

Elective cholecystectomy: 1% severe-complication benchmark

In 48,564 Swedish elective laparoscopic cholecystectomies, achievable-care benchmarks were 0.2% for serious intraoperative events and 1.0% for severe 30-day complications—useful quality targets, not guarantees of what every unit should achieve.