A study of 158 patients with obstructive jaundice in Rwanda revealed endoscopic retrograde cholangiopancreatography (ERCP) as the predominant intervention, achieving a technical success rate of 79.44%. Overall, procedural success reached 82.61%, with percutaneous transhepatic biliary drainage (PTBD) at 91.67% and surgical procedures at 100%. The 30-day survival rate was 92.41%. Notably, weight loss and ICU […]
Category: Surgical Endoscopy
EUS-guided gallbladder drainage shows promising long-term effectiveness
In a comprehensive meta-analysis of 701 patients, endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) achieved an impressive 95.8% technical and clinical success rate for treating acute cholecystitis with over one year of follow-up. This method stands out as a safe and durable alternative, especially for high-risk surgical patients, showcasing a remarkably low rate of adverse events. The […]
Postcolonoscopy colorectal cancers show distinct serrated characteristics
A systematic review of 15 studies reveals postcolonoscopy colorectal cancers (PCCRCs) have notable molecular differences from sporadic colorectal cancers (SCRCs). PCCRCs are more often linked to the serrated pathway, showing higher rates of microsatellite instability (MSI), CPG island methylator phenotype (CIMP), and BRAF mutations, while exhibiting less frequent KRAS mutations. Although their five-year survival rate […]
Endoscopic submucosal dissection outperforms endoscopic mucosal resection
Researchers found that endoscopic submucosal dissection (ESD) offers superior clinical outcomes for early oesophageal cancer compared to endoscopic mucosal resection (EMR). ESD demonstrated a shorter hospitalization time (7.51 vs. 9.16 days) and a significantly better postoperative quality of life. Although ESD surgeries took longer, both techniques achieved comparable resection rates. Importantly, ESD resulted in fewer […]
Emerging endoscopic techniques improve diagnosis and treatment of pancreatic cysts
Accurate diagnosis of pancreatic cystic lesions (PCLs) is critical to avoiding unnecessary surgeries. Despite existing guidelines, many patients with benign cysts still undergo major resections. New endoscopic methods, including advanced imaging and minimally invasive treatments, show promise for enhancing diagnostic precision and offering organ-sparing options. Techniques like endoscopic ultrasound (EUS) and novel therapeutics are well-tolerated […]
New machine learning model predicts cholangitis risk after ERCP
A novel interpretable machine learning model has been developed to predict post-ERCP cholangitis (PEC) in patients with malignant biliary obstruction (MBO). The model, utilizing data from 2831 patients, identified key risk factors including radiofrequency ablation and white blood cell count. Among various machine learning methods, the XGBoost model outperformed others, predicting PEC risk with accuracy […]
New tool predicts perforation risks during endoscopic submucosal dissection
A novel predictive model for perforation risk during endoscopic submucosal dissection (ESD) has been developed and validated by researchers. In a study involving 1,051 patients, significant predictors included the first 100 procedures, lesion size over 35 mm, and extended operative time. The model demonstrated satisfactory validation performance with an area under the curve of 0.7078 […]
Cryopreserved fibroblast sheets reduce esophageal leakage risk
Cryopreserved allogeneic multilayered fibroblast sheets demonstrated efficacy in preventing esophageal anastomotic leakage in a rat model. The incidence of leakage was significantly lower in the fibroblast sheets group (28%) compared to controls (61%; p = .02). Additionally, the burst pressure was notably higher in the sheet group (124 ± 30 mm Hg) versus controls (78 […]
GNAS droplet digital PCR enhances mucinous cyst diagnosis
A single GNAS droplet digital PCR (ddPCR) analysis improves the diagnostic accuracy for mucinous pancreatic cystic lesions (MPCNs) using endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA). Among 140 patients, ddPCR increased MPCN detection to 62% while yielding 100% specificity. The method also identified a third of inconclusive lesions as MPCNs. Importantly, GNAS-ddPCR demonstrated a 24% cost reduction […]
Hydrogels may reduce esophageal stricture risk post-ESD.
Innovative hydrogel interventions show promise in significantly reducing stricture rates following endoscopic submucosal dissection for early esophageal cancer. Current methods have limited effectiveness and safety concerns, but hydrogels offer biocompatibility and enhanced therapeutic delivery. They promote epithelial regeneration and reduce fibrosis, potentially improving long-term outcomes. This review highlights the transformative potential of hydrogels in clinical […]