Innovations in endoscopic resection now enable the safe removal of larger and deeper gastric subepithelial lesions (SELs), previously suitable only for surgical intervention. This article outlines various endoscopic modalities and provides crucial technical tips. In a case series, successful en bloc resections were achieved in all patients with no adverse events, demonstrating the effectiveness of tailored approaches based on lesion evaluation and patient anatomy.
Review by Lajin M, Bazerbachi F, Sohn H and Armas O in VideoGIE
© 2025 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc.