Endoscopic submucosal dissection (ESD) offers better long-term survival than gastrectomy for older patients with early gastric cancer. 5-year overall survival was 85.9% with ESD vs. 80.9% for gastrectomy (p=0.140). In patients aged 80+, gastrectomy had a 3.29 times higher risk of death and a 7.18 times higher risk of gastric cancer-specific death than ESD. Consider […]
Category: Upper Gastrointestinal Tract
Survival Gains in Gastric Cancer with Surgery and Chemotherapy
Surgery combined with chemotherapy significantly improves survival in gastric cancer patients. Median survival for intestinal-type cancers was 45.2 months with surgery and chemotherapy, versus just 5.1 months for palliative treatment. Patients with diffuse-type cancers exceeded 128 months median survival with the same approach, compared to 6.3 months with palliative care. Palliative chemotherapy and radiotherapy also […]
Thoracoscopic surgery improves survival in upper and mid-esophageal cancer
Thoracoscopic esophagectomy outperformed open surgery for upper and middle esophageal squamous cell carcinoma, improving both overall and disease-free survival. In upper tumors, thoracoscopic surgery cut mortality risk by 55% (HR 0.45) and recurrence risk by 45% (HR 0.55). In middle tumors, overall survival improved by 36% (HR 0.64) and disease-free survival by 30% (HR 0.70). […]
Thoracoscopic Oesophagectomy Matches Open Approach in Cancer Patients
Thoracoscopic oesophagectomy is non-inferior to open oesophagectomy regarding overall survival for resectable thoracic oesophageal cancer. 300 patients were studied: 150 underwent open surgery, 150 had the thoracoscopic procedure. At the first interim analysis (1.6 years median follow-up), overall survival was statistically preserved for the thoracoscopic group (HR 0.56). Consider thoracoscopic approaches to enhance patient recovery […]
Surgical Strategies for Proximal Early Gastric Cancer: Dtr and Dft Shine
Surgeons need to know that proximal gastrectomy methods dtr and dft outperform tg and eg in key outcomes for early gastric cancer. Reflux esophagitis rates were higher in eg compared to dft and dtr. Anastomotic stenosis was less common with dtr than eg. Dft achieved the highest 12-month hemoglobin levels; hospital stay was shorter compared […]
Improved Survival Rates for Surgical Gastric Cancer Patients
Conditional relative survival after gastric cancer surgery shows promising results, suggesting better outcomes than previously thought. Five-year conditional relative survival (CRS) rose from 87.2% at one year to 95.4% at five years post-surgery. Stage III patients saw significant improvement, with CRS increasing from 53.2% at one year to 85.2% at five years. Surgery remains a […]
Predicting Postoperative Leakage in Gastrectomy with AI
This study shows that deep learning can predict leakage during laparoscopic gastrectomy for gastric cancer, improving surgical outcomes. Leakage rates were 1.3% at the duodenal stump and 4.3% at the esophagojejunal anastomoses. The ResNet18 model achieved a recall of 84.7% for stump leakage and 80% for anastomosis leakage when trained on high-quality, single-image datasets with […]
ICG imaging elevates surgical outcomes in gastric cancer
Indocyanine green (ICG) guidance improves lymphadenectomy in gastric cancer post-neoadjuvant chemotherapy. ICG increased lymph node retrieval by an average of nearly 9 nodes. Patients with ICG guidance were 2.3 times more likely to retrieve 30 or more nodes compared to conventional methods. ICG use showed no increase in complications, supporting its safe application in surgical […]
Infectious Complications Skyrocket Post-Gastric and Colorectal Surgeries
Postoperative infections in gastric and colorectal cancer surgeries significantly increase costs and hospital stays, demanding urgent attention. 11.8% of surgeries resulted in infections, with 2.2% classified as major. Major infections lead to double the hospitalization costs and triple the length of stay. Surgeons should prioritize prevention strategies for intra-abdominal infections as key risk factors include […]
Predictive Modeling Revolutionizes Post-Gastrectomy Outcomes
Machine learning models effectively predict 30-day mortality after gastrectomy, enhancing surgical decision-making. 4.3% of gastrectomy patients experienced 30-day mortality. The xgboost model outperformed logistic regression and traditional risk calculators, identifying preoperative blood urea nitrogen and age as key predictors. Incorporating these models could significantly improve patient selection and care strategies in your practice. The xgboost […]
