Prioritizing lymphadenectomy and specific surgical approaches improves outcomes in patients with adenocarcinoma of the esophagogastric junction. In a study of 2,044 patients, neoadjuvant therapy lowered lymph node metastasis rates overall. Total gastrectomy resulted in fewer complications (14.8%) compared to proximal gastrectomy (21.0%; p=0.001). Laparoscopic approaches facilitated faster recovery without increasing complications (16.5% vs 17.3%). High […]
Category: Upper Gastrointestinal Tract
Dental Health Has No Impact on Survival After Esophagectomy
Patients’ preoperative dental status does not influence 5-year survival after esophageal cancer surgery. No significant link found between remaining teeth and all-cause mortality at 5 years. Hazard ratios showed no statistical significance across quintiles and deciles of remaining teeth. Dentists’ focus on preserving teeth may not affect surgical outcomes in this population. Journal Article by […]
Multimodal Prehabilitation Reduces Complications in Frail Elderly with Gastric Cancer
A multimodal prehabilitation program improves outcomes for older patients with frailty undergoing radical gastrectomy. Complications dropped significantly in the prehabilitation group (17.2% vs 28.7%; p=0.01). Minor complications were halved (10.7% vs 20.2%; p=0.01), and medical complications also decreased (8.3% vs 16.9%; p=0.02). Patients in the prehabilitation group improved their functional capacity before surgery with an […]
Active Surveillance Offers Quality of Life Benefits in Oesophageal Cancer
Active surveillance after neoadjuvant chemoradiotherapy provides similar survival to surgery while significantly enhancing quality of life for patients with locally advanced oesophageal cancer. Active surveillance patients reported significantly better scores for dysphagia, dyspnoea, fatigue, and physical functioning at 6 months (Cohen’s d of -1.09, -0.63, -0.70, and 0.77, all p ≤ 0.001). Dysphagia improvements were […]
Intrathoracic Side-Overlap Anastomosis Reduces Pain and Reflux
Intrathoracic side-overlap esophagogastrostomy (SOE) shows promise as a viable alternative to circular stapled (CSE) technique in esophagectomy for Siewert type I/II adenocarcinoma. SOE leads to significantly lower postoperative pain scores: 3.49 vs. 4.04 on day one (p=0.002). Severe gastroesophageal reflux is lower with SOE (14.5%) compared to CSE (34.0%) (p=0.019). Dysphagia symptoms are reduced with […]
Robotic Esophagectomy Cuts Nerve Palsy Risk, Outcomes Similar
Robot-assisted minimally invasive esophagectomy (RAMIE) shows lower nerve injury rates compared to conventional minimally invasive esophagectomy (MIE) for esophageal cancer. RAMIE had an operative time of 629 minutes vs. 574 minutes for MIE (p < 0.01). Incidence of recurrent laryngeal nerve (RLN) palsy was 22% with RAMIE vs. 34% with MIE (p = 0.02). Both […]
Laparoscopic Antireflux Surgery Outperforms Robotic Approach
Robotic-assisted antireflux surgery shows less cost-effectiveness compared to laparoscopic methods. Robotic surgery costs significantly more: $15,676 vs. $7,694. Operating room time is longer with robotic surgery (169 min vs. 128 min). Surgeons should reconsider the use of robotic techniques for antireflux surgery due to higher costs and similar outcomes. Intraoperative complications were slightly higher with […]
Esophagectomy vs Active Surveillance: Long-Term Outcomes for Esophageal Cancer
Active surveillance may be a viable option for select esophageal cancer patients achieving clinical complete response after neoadjuvant chemoradiation, but esophagectomy secures superior long-term survival. At 5 years, standard esophagectomy outperformed active surveillance with 1.74 vs 1.34 quality-adjusted life-years (QALYs) and 3.11 vs 2.41 life-years. Active surveillance showed short-term benefits, with a 2-year QALY gain […]
Early Feeding Safe After Esophagectomy for Cancer Patients
Early oral feeding after esophagectomy is safe and leads to better recovery outcomes. No increase in anastomotic leakage (risk ratio 0.89) noted. Early feeding significantly reduces pneumonia (risk ratio 0.66) and accelerates gastrointestinal recovery—first bowel movement and flatus occur about half a day earlier. Hospital stays shortened by nearly two days (1.89 days) with associated […]
Minimally invasive total gastrectomy matches open approach for cancer
Minimally invasive total gastrectomy (MITG) is as effective as open total gastrectomy (OTG) for locally advanced gastric cancer. 5-year overall survival rates: MITG at 87.3% vs. OTG at 83.0% (p = 0.398) Complication rates similar: MITG 10.6% vs. OTG 12.4% (p = 0.470) Consider MITG for suitable patients, balancing its lower blood loss with longer […]
