J Gastric Cancer29 Jan 2025
The 2023 nationwide survey by the Korean Gastric Cancer Association revealed that early gastric cancer comprised 63.1% of cases. Notably, the mean patient age increased to 64.6 years, with those aged ≥71 rising to 31.7% since 1995. The use of totally laparoscopic surgery was predominant…
J Gastric Cancer28 Jan 2025
The 2024 Korean Practice Guidelines for Gastric Cancer present significant updates, particularly in systemic treatment, following a thorough review by an interdisciplinary team. Six key questions were revised, and seven statements developed based on extensive systematic reviews and recent research. The updated guidelines aim to…
Upper Gastrointestinal Tract28 Jan 2025
Function-preserving gastrectomy (FPG) techniques, such as pylorus-preserving and proximal gastrectomy, effectively balance oncological safety while enhancing patients' quality of life (QoL) following early gastric cancer treatment. These methods yield comparable oncological outcomes to traditional surgery and promote better nutritional recovery with fewer gastrointestinal issues. However,…
World J Gastrointest Oncol27 Jan 2025
The study developed a novel prognostic model for overall survival in esophageal carcinoma (EC) patients, incorporating nine significant predictors, including body mass index and treatment modalities. Tested on 3,127 patients, the model achieved a c-index of 0.715 in training and 0.711 in validation cohorts. Area…
Appendix, Gallbladder and Surgical Emergencies27 Jan 2025
The study reveals that laparoscopic omental patch repair (LOPR) offers significant advantages for treating Helicobacter pylori-associated gastric ulcers with perforations. Patients undergoing LOPR demonstrated reduced operative time, less intraoperative blood loss, and quicker postoperative recovery compared to those receiving the Graham patch technique. Additionally, LOPR…
Int J Surg24 Jan 2025
Bolus exposure demonstrated superior predictive capability for postoperative symptom resolution in patients undergoing laparoscopic Nissen fundoplication, outshining traditional acid-based parameters. In a cohort of 72 gastroesophageal reflux disease patients, its diagnostic accuracy reached 0.981 for regurgitation and 0.723 for epigastric pain. Secondary analyses in patients…
J Gastrointest Surg23 Jan 2025
A study involving 335 gastric cancer patients undergoing radical surgery found significant declines in skeletal muscle mass index (SMI), skeletal muscle density (SMD), and subcutaneous adipose tissue (SAT) during the perioperative period. Factors such as age ≥65 and low handgrip strength increased the risk of…
Upper Gastrointestinal Tract22 Jan 2025
An updated meta-analysis involving 11,981 gastric cancer patients revealed that preoperative sarcopenia is linked to substantial postoperative complications, including increased rates of mortality, readmission, and severe complications. Sarcopenic patients exhibited notably higher incidences of pulmonary issues, bowel obstructions, and pancreatic fistulas, leading to significantly poorer…
J Surg Oncol21 Jan 2025
Among 4,429 patients undergoing gastric adenocarcinoma resection (2016-2022), minimally invasive surgery (MIS) was linked to lower complication rates compared to open gastrectomy, with fewer major complications (13.1% vs. 18.5%) and reduced perioperative mortality (0.57% vs. 1.53%). Despite these benefits, MIS utilization remained stagnant, indicating a…
Surgical Endoscopy21 Jan 2025
Recent advancements in peroral flexible endoscopy improve approaches to managing gastric subepithelial tumors (SETs) with malignant potential. Resection techniques depend on tumor size, with options like endoscopic mucosal resection for superficial lesions and endoscopic enucleation for small tumors. When full-thickness resection is complex, laparoscopic and…