Surg Endosc19 Jan 2025
A nomogram created to forecast lymph node metastasis (LNM) in submucosal early gastric cancer (EGC) shows significant predictive accuracy. Analyzing data from 389 patients, the model employs risk factors like gender, CA199 levels, and tumor traits, achieving an area under the curve of 0.82 in…
Dis Esophagus19 Jan 2025
A systematic review and meta-analysis of six randomized clinical trials involving 850 patients highlights the benefits of enhanced recovery after surgery (ERAS) protocols following oesophagectomy. The analysis showed significantly reduced overall complication rates, pulmonary complications, and shorter post-operative length of stay and time to flatus…
J Clin Med18 Jan 2025
Recurrent laryngeal nerve palsy remains a major complication after minimally invasive esophagectomy for esophageal cancer. Despite advancements, incidence rates have not improved significantly. The review examines prevention strategies such as nerve integrity monitoring and robotic surgery, which show varied effectiveness. Management techniques include voice rehabilitation…
Endoscopy16 Jan 2025
A modified double-layered suturing method, known as the origami method, demonstrated a 96% success rate in achieving complete closure of large mucosal defects following duodenal endoscopic submucosal dissection (ESD). In a review of 28 cases, closure was completed with a median time of 16 minutes,…
Am J Gastroenterol15 Jan 2025
A systematic review of 1,899 articles identified 30 relevant studies on gastric peroral endoscopic myotomy (GPOEM) for refractory gastroparesis. Findings revealed a GPOEM response rate of 63.1%. Key predictors for a positive response included older age, shorter gastroparesis duration, nondiabetic etiology, lower body mass index,…
Gut Liver12 Jan 2025
A study analyzing 69 patients with gastric neuroendocrine tumors (GNETs) showed a favorable prognosis, with 5-year survival rates at 93.8% and recurrence rates at 7.25%. Most tumors were grade 1 and type I, with treatment variations between tumor grades; grade 1 patients often opted for…
Ann Surg Oncol11 Jan 2025
A multicenter study identified early recurrence (ER) within two years post-surgery in 15% of 11,615 gastric cancer patients. Utilizing machine learning, researchers developed a stacking ensemble model that achieved an area under the receiver operating characteristic curve of 1.0 for training and 0.8 for testing,…
Upper Gastrointestinal Tract10 Jan 2025
A nationwide study in Finland found that patients undergoing gastrectomy at university hospitals experience lower short-term and long-term mortality rates compared to those treated at nonuniversity hospitals. An analysis of 10,455 patients from 1987 to 2016 indicated that university hospital patients were younger and had…
Eur J Surg Oncol9 Jan 2025
Multimodal prehabilitation significantly improved physical capacity and reduced chronic inflammation in frail elderly patients undergoing gastric cancer surgery. The intervention, encompassing physical training, nutritional support, and psychosocial treatment over two weeks, resulted in a mean 6-min walk test change of +28 meters (p < 0.001).…
BMC Surg8 Jan 2025
A new predictive model utilizing machine learning has shown promise in forecasting duodenal stump leakage after laparoscopic gastrectomy for gastric cancer. Analyzing data from 4,070 patients, the support vector machine emerged as the most effective algorithm, achieving high sensitivity, accuracy, and specificity. Key factors influencing…