A significant majority of patients (84.1%) underwent same-day discharge following minimally invasive Heller myotomy, with rates improving from 58% to over 90% in successive quartiles. The study, involving 157 patients, reported a low overall complication rate of 2.6%, with no fatalities or reinterventions. Reasons for delayed discharge included patient preference and surgeon discretion. These findings […]
Category: Upper Gastrointestinal Tract
Occult metastases detected in 20.7% of gastric cancer patients
A retrospective analysis involving 232 patients undergoing staging laparoscopy (SL) revealed that 20.7% had occult metastases. Peritoneal carcinomatosis was the most common, affecting 17.2% of patients, followed by liver metastases. Key risk factors identified included positive cytology at staging (cm-positivity) and the presence of signet ring cells, both confirmed through multivariate analysis. The findings emphasize […]
Japan’s esophageal cancer survival rates highlight treatment effectiveness
In Japan, a comprehensive registry observed 9,593 esophageal cancer cases in 2016, revealing significant variations in 5-year survival rates by treatment type. Endoscopic resection yielded the highest survival at 89%, followed by esophagectomy at 59%. Notably, minimally invasive esophagectomy was preferred in 65.1% of cases. Tumor stage profoundly impacted outcomes, with 83% survival in stage […]
Psychological and sleep interventions enhance recovery in gastric cancer patients
A study involving 198 postoperative gastric cancer patients reveals a structured psychological and sleep enhancement program significantly reduces anxiety, depression, and perceived stress while improving sleep quality. After three months, immune function and inflammatory markers also showed notable improvements. Patients in the intervention group experienced better disease-free survival rates (81.2% vs. 68.5%) and overall survival […]
Novel surgical technique preserves ghrelin secretion in gastric cancer
A new surgical approach, super subtotal gastrectomy (SSTG), effectively preserves the fornix, a vital site for ghrelin secretion, in patients with upper-third gastric cancer. This innovative technique minimizes the typical impacts on appetite and weight loss associated with traditional proximal gastrectomy or total gastrectomy. In the SSTG group, procedures averaged 333 minutes with minimal blood […]
Hydrogels may reduce esophageal stricture risk post-ESD.
Innovative hydrogel interventions show promise in significantly reducing stricture rates following endoscopic submucosal dissection for early esophageal cancer. Current methods have limited effectiveness and safety concerns, but hydrogels offer biocompatibility and enhanced therapeutic delivery. They promote epithelial regeneration and reduce fibrosis, potentially improving long-term outcomes. This review highlights the transformative potential of hydrogels in clinical […]
Conversion surgery enhances survival in advanced gastric cancer patients
In a multicenter study of 232 patients with stage IV HER2-positive gastric cancer, conversion surgery following trastuzumab-based chemotherapy and immunotherapy yielded significantly improved outcomes. Patients who underwent the procedure experienced median progression-free survival of 37.7 months and overall survival of 50.9 months. In contrast, those who did not have surgery had progression-free survival of 10.8 […]
AI Enhances Real-Time Detection of Nerve Traction During Surgery
A novel AI system demonstrated effectiveness in real-time detection of excessive traction on the recurrent laryngeal nerve during robotic-assisted esophagectomy. In a pilot study, the AI accurately identified potential nerve damage in 84.4% of surgical scenes, providing crucial feedback earlier than conventional monitoring methods. This proactive approach could facilitate timely adjustments in surgical technique, helping […]
Advanced machine learning outperform traditional models in gastric cancer prognosis
A new machine learning framework combined with a nomogram has been developed to predict recurrence after radical gastrectomy in patients with non-metastatic gastric cancer and “double invasion.” Among the 559 patients studied, the random survival forests model achieved the highest c-index of 0.791, outperforming other machine learning approaches. This hybrid model effectively integrates multiple variables […]
AI Model Matches Senior Endoscopists in Esophageal Cancer Treatment
An artificial intelligence model developed for marking detection and incision guidance during esophageal endoscopic submucosal dissection (ESD) demonstrated promising performance. Compared to junior endoscopists, the AI achieved a notable accuracy of 63.21%, precision rates of up to 85.76%, and an average distance error of 0.096, significantly outperforming junior practitioners while matching senior endoscopists. These results […]