Category: Upper Gastrointestinal Tract

Endoscopic Submucosal Dissection Outperforms Mucosal Resection for Barrett’s Neoplasia

Endoscopic submucosal dissection (ESD) yields superior en bloc resection, higher R0 resection, and curative resection rates compared to endoscopic mucosal resection (EMR) for Barrett’s neoplasia and esophageal adenocarcinoma. ESD also shows lower local recurrence rates. Adverse events between the two techniques were similar. These findings suggest that ESD may be a more effective approach in […]

Proximal Gastrectomy with Double-Tract Reconstruction Reduces Glucose Spikes

Proximal gastrectomy with double-tract reconstruction leads to lower glucose variability postoperatively compared to total gastrectomy. Patients who underwent the procedure exhibited smaller fluctuations in glucose levels and experienced fewer dumping symptoms. Food flow into the remnant stomach was crucial for maintaining better glycemic control and preventing dumping syndrome. This study highlights the benefits of proximal […]

Novel Technique for Esophageal Reconstruction: OVEA

A novel oral-vestibule-enteral anastomosis (OVEA) technique shows promise in patients with compromised epiglottic function or esophageal loss, providing a solution where traditional surgeries fail. Outcomes from 13 patients revealed successful oral feeding, improved quality of life, and minimal fatalities, highlighting the potential of OVEA to enhance patient outcomes. Further research is needed to assess long-term […]

Preoperative Lab Indicators Predict Survival in Esophageal Carcinoma

Preoperative laboratory data indicators, including the systemic immune-inflammation index (SII) and prognostic nutritional index (PNI), were found to significantly impact overall survival in patients with postoperative staged T3N0M0 esophageal carcinoma. These indicators, along with the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and lymphocyte-to-monocyte ratio (LMR), were identified as independent predictors of prognosis. Combining SII and […]

Robotic Surgery Shows Superiority Over Laparoscopic Surgery in Gastric Cancer Treatment

Robotic gastrectomy (RG) demonstrated higher overall survival, lower postoperative complications, faster recovery, and other advantages compared to laparoscopic gastrectomy (LG) in gastric cancer patients. While mortality and disease-free survival were similar between the two techniques, RG offered better outcomes in specific scenarios like intracorporeal reconstruction and certain stages of cancer. These findings support the use […]

Endoscopic Resection Clinical Algorithm

Malignancies in the upper gastrointestinal tract can be effectively treated through endoscopic resection at an early stage. Key factors influencing successful resection include thorough pre-resection assessment, precise delineation of margins, and selection of appropriate resection techniques. This review outlines clinical algorithms for the endoscopic resection of esophageal squamous cell carcinoma, Barrett’s neoplasia, and gastric neoplasia, […]

Low-cost Elastic Organ Retractor for Bariatric Surgery

In minimally invasive upper gastrointestinal and bariatric surgery, a trocar-less elastic intra-corporeal retractor (icr) was developed and proven effective in liver retraction. The icr is safe, inexpensive, and easily reproducible, reducing risks of bleeding, infection, and liver injury associated with conventional methods. It offers quick application and repositioning, enhancing surgical precision and safety in around […]

Enhanced Gastric Cancer Staging Using New N Classification System

This study developed and validated a new lymph nodal staging system for pt3-4n0-2m0 gastric cancer patients. The new classification, based on examined lymph nodes and lymph node ratio, outperformed the current system in prognostic prediction accuracy. The improved staging method emerged as an independent prognostic indicator, providing enhanced survival analysis for patients. Surgeons are encouraged […]

Proton-Based Therapy Equivalent to Surgery for Esophageal Cell Carcinoma

A multi-center study in Japan found that proton-based definitive chemoradiotherapy (p-crt) showed equivalent 3-year overall survival (OS) compared to neoadjuvant chemotherapy followed by esophagectomy (nac-s) in esophageal squamous cell carcinoma patients. While the p-crt group had inferior progression-free survival (PFS), there was better survival in cases of progression, particularly among those with ct1-2 and cstage […]

Nomogram predicts survival in esophageal squamous cell cancer

A nomogram incorporating radiomics and dosiomics features, along with clinical factors, was developed to predict overall survival in esophageal squamous cell carcinoma (ESCC) patients undergoing definitive chemoradiotherapy. Dosiomics features outperformed radiomics features in predicting survival outcomes. The combined model exhibited significant differences in overall survival between high- and low-risk groups, highlighting its potential for personalized […]