A national cohort study validated the external validity of the MIRO randomized controlled trial in a real-life population within France by comparing postoperative complications in esophageal cancer patients. The hybrid approach was found to be protective against severe respiratory complications, with no significant difference in 30-day mortality or leakage rate between surgical approaches. Journal Article […]
Category: Upper Gastrointestinal Tract
Low Rates of Metastases in Mucosal Esophageal Adenocarcinoma with Poor Differentiation
Patients with mucosal esophageal adenocarcinoma and poor differentiation had low rates of metastases after endoscopic resection, even when additional risk factors were present. Metastasis rates were 4.0% for single risk factor patients and 20.0% for those with additional risk factors. Overall death rates were 28.0% and 20.0% for the respective groups. A conservative approach may […]
Esophagectomy improves 5-year overall survival in locally advanced esophageal adenocarcinoma
Esophagectomy is associated with improved 5-year overall survival in locally advanced esophageal adenocarcinoma. Factors like age, race, treatment location, insurance, and tumor size influence esophagectomy use. Non-surgical treatment, government insurance, low income, non-academic centers, comorbidities, and larger tumors increase the risk of all-cause mortality. Esophagectomy and systemic therapy decrease mortality risk. Patients undergoing esophagectomy had […]
Robotic Surgery Shows Promising Results for Resectable Esophageal Cancer
Robotic surgery in esophagectomy for resectable esophageal cancer offers advantages such as reduced postoperative pain and pulmonary complications. A review of 113 studies shows that outcomes include a weighted mean postoperative pneumonia rate of 11%, anastomotic leak rate of 10%, and a 95% success rate in achieving a clear resection margin. There is a potential […]
Spectral CT and Machine Learning Improve Preoperative Prediction of Gastric Cancer Invasion
Accurate preoperative prediction of lymphovascular and perineural invasion status in gastric cancer patients is crucial for identifying high-risk individuals. This study developed and tested a machine learning model that successfully combines spectral CT parameters and clinical indicators to accurately predict LVI/PNI status. The integration of portal venous and ep spectral CT parameters significantly enhances the […]
Extended 96-hour Acid Reflux Monitoring Diagnosed More Patients with GERD Compared to Standard 48-hour Testing
Prolonged acid reflux monitoring for 96 hours diagnosed more patients with GERD compared to standard 48-hour testing. Extended monitoring led to clinically significant changes in study interpretation, with almost half of patients showing abnormal results after a normal study on day 1. Results suggest that only monitoring for 48 hours may miss a diagnosis of […]
Improved Esophageal Cancer Response Assessment with Early Contrast-Enhanced MRI
Early contrast-enhanced MR imaging showed higher accuracy in detecting complete tumor response in esophageal squamous cell carcinoma post-neoadjuvant therapy compared to T2WI+DWI. ECE-MRI had an AUC of 0.85 for diagnosing ypt1-4, significantly better than T2WI+DWI. Performance improved with increasing tumor stage, with higher AUCs in ypt1 and ypt2 tumors. ECE-MRI visual evaluation is promising for […]
Safe and Effective Robot-Assisted Gastric Resection: 5-Year Clinical Outcome
Robot-assisted endoscopic full-thickness gastric resection with regional lymph node dissection using a 3D near-infrared video system resulted in no metastasis or mortality in patients with early gastric cancer over a 5-year follow-up period. This approach may be a safe and effective method for radical gastrectomy in such patients, highlighting the potential benefits of this technique […]
Endoscopic Vacuum Therapy Shortens Treatment Duration for Esophageal Perforations
Patients with traumatic esophageal perforations treated with endoscopic vacuum therapy (evt) had significantly shorter treatment duration than those treated with endoscopic self-expandable metal stent (e-sems). However, e-sems led to a shorter time of hospitalization and lower costs. Both methods had similar clinical outcomes, with high discharge rates. Journal Article by de Oliveira AT, Barreira MA […]
Spigelman Staging System: Predicting Duodenal and Papillary Cancer Risk in Familial Adenomatous Polyposis
Individuals with familial adenomatous polyposis (FAP) have a 25% risk of duodenal and papillary cancers once duodenal polyposis reaches Spigelman stage IV, although the sensitivity of this stage is low. Factors like polyp size, count, and dysplasia influence cancer risk. The Spigelman staging system lacks specific variables for papillary cancer, suggesting a need for updates […]