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Upper Gastrointestinal Tract

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Gastrointest Endosc10 Sep 2024

Endoscopic Vacuum Therapy effectively treats Boerhaave’s syndrome.

A multicenter analysis demonstrates that Endoscopic Vacuum Therapy (EVT) has a high success rate for treating Boerhaave's syndrome, yielding an 80% treatment success in 25 patients. Mortality rates were significantly lower for EVT patients (8.0%) compared to those undergoing other methods (25.0%). Moreover, treatment success…

Dig Endosc10 Sep 2024

Endoscopic submucosal dissection proves more effective than EMR

A systematic review and meta-analysis involving 9,352 patients reveals that endoscopic submucosal dissection (ESD) outperforms endoscopic mucosal resection (EMR) in effectively treating early Barrett's neoplasia. ESD achieved significantly higher en-bloc resection rates (odds ratio 25.96) but was associated with greater incidence of adverse events. The…

Ann Surg9 Sep 2024

Early esophago-gastric adenocarcinoma linked to high lymph node metastasis risk

A multicenter study involving 1,601 patients revealed a 13.5% incidence of lymph node metastasis (lnm) in early esophago-gastric adenocarcinoma. Factors such as tumor depth and lymphovascular invasion showed initial associations with lnm but lacked significance in multivariable analyses. Notably, surgery following endoscopic resection significantly improved…

Ann Surg Oncol9 Sep 2024

Postoperative insulin resistance worsens recovery after gastrectomy.

A cohort study involving 60 gastric cancer patients revealed that postoperative insulin resistance significantly worsens short-term recovery after radical gastrectomy. Key findings indicated increased insulin resistance and inflammation, along with decreased nutritional markers. The gut microbiome showed notable changes, including reduced bifidobacterium and butyrate levels.…

Appendix, Gallbladder and Surgical Emergencies8 Sep 2024

High neutrophil-lymphocyte ratio indicates increased mortality risk in UGIB patients

A study involving 726 patients with upper gastrointestinal bleeding (UGIB) revealed that a high neutrophil-lymphocyte ratio (NLR) on admission significantly predicts in-hospital mortality risk. Researchers found that while 6% of patients died, 23.9% required endoscopic intervention, and 46.4% needed blood transfusion. The integration of NLR…

Dig Endosc7 Sep 2024

Endoscopic hand suturing significantly reduces postoperative bleeding risk.

A multicenter phase II study demonstrates that endoscopic hand suturing (EHS) effectively reduces the postoperative bleeding rate to 7% in patients undergoing gastric endoscopic submucosal dissection while on antithrombotic agents. Out of 43 patients analyzed, the EHS method achieved a 100% technical success rate and…

Med Sci Monit6 Sep 2024

Use of S-O Clips Reduces Procedure Time in Gastric ESD

S-O Clips Improve Gastric ESD Efficiency and Resection Rates In a retrospective analysis of 290 patients with early gastric neoplasms, the use of spring-and-loop clips (S-O clips) in endoscopic submucosal dissection (ESD) significantly reduced procedure time (44.4 vs 61.1 minutes, p

Surg Endosc5 Sep 2024

A novel phoenix score reduces inconclusive GERD diagnoses

The development of the phoenix score significantly improved the classification of gastroesophageal reflux disease (GERD) cases. Among patients with total acid exposure time (AET) from 2 to 6%, the phoenix score decreased inconclusive diagnoses from 77.2% to 13.2% (p < 0.001). With an AUC of…