High-risk gastric cancer patients may benefit from limited lymph node dissection (LND), while standard LND improves relapse-free survival in low-risk patients. Limited LND reduces postoperative complications in low-risk patients, without affecting outcomes in high-risk patients. Pancreatic fistula was not observed in the limited dissection group, suggesting it may be the optimal treatment for high surgical […]
Category: Upper Gastrointestinal Tract
Octreotide does not improve outcomes in adult patients with post-esophagectomy chylothorax
Octreotide’s efficacy in managing intrathoracic chyle leak post-esophagectomy in adults was investigated in a cohort study. Among 74 patients, 27 received octreotide, but there was no significant difference in chest tube duration, hospital length of stay, or overall survival compared to non-octreotide group. Multivariable analysis confirmed that octreotide did not affect clinical outcomes. The study […]
Prognostic value of tumour response and nodal status in oesophageal adenocarcinoma
Researchers found that higher Mandard score and residual nodal disease were associated with increased recurrence rates and worse overall survival in patients with oesophageal adenocarcinoma. Patients with better tumour response (trg1) had lower recurrence rates and longer overall survival compared to those with poorer response (trg>1). Residual nodal disease had a more negative impact on […]
Identification of Promising Prediction Models for Morbidity and Mortality After Esophagectomy
A systematic review identified 33 prediction models for morbidity and mortality after esophagectomy, with 18 newly developed. Prognostic accuracy ranged from 0.51 to 0.85, with some models showing promise for further development. Performance status emerged as a potential modifiable risk factor, but none of the models are ready for clinical implementation. Two models for mortality […]
Task-Specific Metrics for Laparoscopic Fundoplication in Hiatal Hernia Repair
Researchers successfully developed and validated task-specific metrics (TSM) for laparoscopic Nissen fundoplication, a critical phase in laparoscopic hiatal hernia repair (LHHR). Utilizing structured interviews with expert foregut surgeons and a simulation involving participants with varying surgical expertise, the study demonstrated high interrater reliability and significant validity evidence for both global and TSM assessments. These LHHR-specific […]
Esophageal Washout with Povidone-Iodine Reduces Intraluminal Tumor Cells in Carcinoma Resection
Intraoperative esophageal washout with povidone-iodine solution significantly reduces the presence of free intraluminal tumor cells during esophageal and cardiac carcinoma resection. Neoadjuvant treatment decreases the likelihood of malignant cells in the esophagus. Repetitive washout decreases detectable malignant cells, with a significant reduction after 10 maneuvers. This novel, feasible procedure can help eliminate tumor cells and […]
ICG-Guided Lymphadenectomy in LAGC: RCT Results
Indocyanine Green (ICG)-guided lymph node (LN) dissection during laparoscopic radical gastrectomy significantly improves the quality of lymphadenectomy in locally advanced gastric cancer (LAGC) patients post-neoadjuvant chemotherapy (NAC). A randomized controlled trial with 236 patients demonstrates that ICG increases LN retrieval and decreases non-compliance rates, particularly in cases without baseline measurable LNs and in those with […]
PORSHA for Paraesophageal Hernias: Phase 2a Results
Posterior Rectus Sheath Hiatal Flap Augmentation (PORSHA) exhibits promise as a surgical innovation for large and recurrent paraesophageal hernias. In a study of 27 cases, PORSHA, after technical modifications, demonstrated safety and success in repairing type III, IV, and recurrent paraesophageal hernias. At an 11-month follow-up, there were no radiologic recurrences, abdominal eventrations, or hernias […]
TSLG versus LTH for Siewert Type II AEG: Advantages and Efficacy
Transthoracic single-port-assisted laparoscopic gastrectomy (TSLG) demonstrates technical safety and feasibility in comparison to laparoscopic transhiatal approach (LTH) for Siewert type II adenocarcinoma of the esophagogastric junction. In a retrospective study, TSLG showed advantages, including increased harvested lymph nodes, reduced lower mediastinal lymph nodes, and longer proximal margins. The R0 gastrectomy rate was higher in the […]
Recurrence-Free Survival Strongly Correlates with Overall Survival in Neoadjuvant-Treated Oesophageal Squamous Cell Carcinoma
Recurrence-free survival is a valid surrogate endpoint for overall survival in surgically resectable advanced oesophageal squamous cell carcinoma (oscc) patients receiving neoadjuvant chemotherapy. A strong correlation (kendall’s τ 0.797) was found between the two endpoints, particularly in patients with a more favorable response to neoadjuvant treatment. This suggests that recurrence-free survival can be used as […]
