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Upper Gastrointestinal Tract

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J Gastrointest Surg5 Apr 2024

Proximal gastrectomy may be an alternative approach for well-selected patients with proximal gastric cancer following neoadjuvant chemotherapy

Study comparing total and proximal gastrectomy for proximal gastric cancer found that more patients underwent proximal gastrectomy, with a higher likelihood of receiving neoadjuvant chemotherapy. Pathologically, total gastrectomy patients had more advanced tumors and fewer evaluated lymph nodes, but lower margin negativity. Long-term survival did…

J Gastrointest Surg5 Apr 2024

Impact of Preoperative Anemia on Outcomes in GEP-NET Resections

Patients with preoperative anemia undergoing curative-intent resection for gastroenteropancreatic neuroendocrine tumors (GEP-NETs) had higher rates of major complications and poorer long-term outcomes. Anemia was associated with worse overall survival, while postoperative transfusions were linked to lower overall survival and recurrence-free survival rates. Preoperative anemia affected…

J Gastrointest Surg5 Apr 2024

ERAS Protocol Reduces Hospital Stay in Gastric Cancer Surgery

Implementation of enhanced recovery after surgery (ERAS) protocol in distal gastrectomy for gastric cancer significantly reduces adjusted hospital stay without increasing complications. However, no significant differences were observed in long-term nutritional outcomes and quality of life between ERAS and conventional care groups

Ann Surg Oncol4 Apr 2024

Potent Nomogram Predicts Lymph Node Involvement in Early Gastric Cancer

A potent nomogram incorporating tumor budding accurately predicts lymph node involvement in early gastric cancer patients, providing exceptional discriminative power and precise predictive capabilities. Tumor budding, along with other clinicopathological factors, demonstrated a robust association with lymph node involvement, improving clinical decision-making by reducing the…

BMC Surg4 Apr 2024

Superior Outcomes of Modified Billroth-II in Gastric Cancer Reconstruction

Comparing modified Billroth-II with hinged anti-peristaltic afferent loop and Roux-en-Y reconstruction after distal gastrectomy for gastric cancer, the former showed superior outcomes in terms of operating time, postoperative hospital stays, and time to semi-solid diet tolerance. However, both methods had similar functional outcomes. The study…

Ann Surg Oncol3 Apr 2024

Impact of Neoadjuvant Immunotherapy on Perioperative Outcomes in Esophageal Adenocarcinoma

Patients with locally advanced esophageal adenocarcinoma who received neoadjuvant immunotherapy (io) combined with chemotherapy showed similar perioperative outcomes compared to those who received neoadjuvant chemotherapy alone. Rates of overall and major complications, anastomotic leak, respiratory complications, hospital stay length, and mortality were comparable between the…

Surg Endosc3 Apr 2024

Frequency of size increase in gastric leiomyomas is low

Most gastric leiomyomas are benign subepithelial tumors, with few becoming symptomatic or increasing in size. A retrospective review of 231 cases showed that only 2.4% experienced size increase, one of which was leiomyosarcoma. The majority remained stable, with resections confirming leiomyoma. Close monitoring may be…