A multi-institutional retrospective study investigated the clinical impact of conversion surgery for esophageal cancer with synchronous distant metastasis after induction therapy. Out of the 66 enrolled patients, distant lymph node metastasis occurred in 77%, while distant organ metastasis occurred in 23%. The study found that conversion surgery after chemotherapy or chemoradiotherapy is feasible and may […]

Age should not be a contraindication to esophagectomy for cancer treatment, according to the results of an international multicenter retrospective analysis. The study included 575 patients who underwent esophagectomy between 2007 and 2016 and found that postoperative mortality increased with age, from 2% in younger patients to 4.8% in older patients. However, disease-free and disease-related […]

Male sex and Roux-en-Y reconstruction were identified as independent risk factors for abdominal surgical infectious complications (ASIC) after distal gastrectomy for gastric cancer. A post-hoc analysis of a randomized controlled trial (JCOG0912) found that male patients had a 2.364 times higher risk of developing ASIC, and those who underwent Roux-en-Y reconstruction had a 2.310 times […]

Researchers conducted a retrospective study to compare the outcomes and safety of different chemotherapy regimens as perioperative treatment in elderly patients with resectable gastric cancer. They found that the Flot and DCF regimens were associated with longer overall survival compared to other regimens, with Flot showing the most significant improvement. Additionally, the DCF regimen had […]

Researchers conducted a study to examine the influence of a randomized controlled trial (RCT) on the practice and outcomes of laparoscopic gastrectomy in the Netherlands. The RCT included 10 Dutch centers and compared laparoscopic to open gastrectomy. Data analysis showed that there was no significant effect on clinical outcomes within the RCT itself. However, nationally, […]

Researchers conducted a cohort study involving 4688 patients with esophageal cancer to develop an optimized postsurgery follow-up strategy. By using recursive partition analysis and a random survival forest, patients were stratified into four groups based on pathological features, with surveillance strategies developed for each group. These strategies were validated and found to outperform mainstream guidelines […]

The study aimed to compare the incidence of bile reflux, quality of life (QOL), and nutritional status among different reconstruction methods after laparoscopic distal gastrectomy. The results showed that Roux-en-Y reconstruction had the lowest incidence of bile reflux, followed by Billroth II with Braun anastomosis, and then Billroth II. Billroth II with Braun anastomosis was […]

R Anastomosis, a novel technique for B-II-B anastomosis during laparoscopic distal gastrectomy, was compared to conventional anastomosis in a propensity score matching analysis. The study included 246 patients, with 123 in each group. The R group had significantly reduced anastomotic time, and there were no intraoperative complications, conversions to open surgery, or perioperative mortalities reported […]

A prospective randomized trial compared two methods of lymphadenectomy along the left recurrent laryngeal nerve (lrln) during minimally invasive esophagectomy in esophageal squamous cell carcinoma patients. The retraction method (rm) was found to be more beneficial, as it reduced surgical duration significantly compared to the suspension method (sm). There were no differences in postoperative complications, […]