Dysphagia9 Feb 2024
Researchers conducted a comprehensive analysis using big data to investigate the frequency of hiatus hernia (hh) and its association with esophageal disorders. They reviewed endoscopic reports of over 75,000 patients and found that hh was present in 16.8% of cases, with the majority being small…
Ann Surg Oncol7 Feb 2024
A retrospective study analyzed the outcomes of patients with resectable locally advanced esophageal squamous cell carcinoma (LA-ESCC) who underwent neoadjuvant chemoradiotherapy. Researchers found that tumor shrinkage rate is an independent prognostic factor for progression-free survival (PFS). For patients who responded to treatment, extending the time-to-surgery…
J Surg Res7 Feb 2024
A retrospective analysis evaluated the effectiveness of the manual layered insertion anastomosis technique in reducing anastomotic leakage post-esophagectomy. The study included 56 patients who underwent this technique, all receiving minimally invasive esophagectomy. With no reported anastomotic leakages, the technique showed potential in reducing complications such…
J Surg Res6 Feb 2024
The Comprehensive Complication Index (CCI) showed a stronger positive association than the Clavien-Dindo Classification (CDC) with short-term postoperative complications in patients with gastric cardia adenocarcinoma. The CCI demonstrated superior correlation strength for hospital length of stay, duration of ICU stay, time to return to normal…
Ann Surg Oncol5 Feb 2024
The study included 717 patients and found that the new muscle parameter, SMG, obtained by multiplying the skeletal muscle index (SMI) and skeletal muscle radiation attenuation (SMRA), can predict the prognosis of patients with gastric cancer. The findings showed that SMG can effectively predict both…
Ann Surg4 Feb 2024
Analysis of the SENORITA trial comparing laparoscopic standard gastrectomy (LSG) and laparoscopic sentinel node navigation surgery (LSNNS) for early gastric cancer (EGC) found that there was no significant difference in the 5-year disease-free survival (DFS), overall survival (OS), or disease-specific survival (DSS) between the two…
Dis Esophagus3 Feb 2024
Among 97 patients with non-curative endoscopic resection (ER) for esophageal squamous cell carcinoma (ESCC), 73 underwent additional chemoradiotherapy (CRT). With a median follow-up of 71 months, recurrences were observed in 14% of patients. Lymphatic invasion was identified as an independent risk factor for recurrence. Notably,…
BMC Surg3 Feb 2024
The main result of this study is that preoperative and postoperative serum CA19-9 values are independent risk factors for predicting the prognosis in patients with stage III gastric cancer after curative gastrectomy. Patients with CA19-9 levels greater than 35 U/ml had significantly lower recurrence-free survival…
Upper Gastrointestinal Tract2 Feb 2024
Gastroesophageal reflux disease (GERD) is a common condition with increasing prevalence worldwide and a high economic burden. Despite proton pump inhibitor (PPI) therapy, a significant number of patients remain symptomatic. This review highlights the importance of differentiating between unproven GERD and refractory GERD, and provides…
Ann Surg Oncol31 Jan 2024
Approximately 4-9% of patients had a tumor-positive resection margin after neoadjuvant chemoradiotherapy (ncrt) and esophagectomy. Only a small proportion of patients received adjuvant therapy, despite the association of positive margins with decreased survival. However, a real-world study revealed that 61% of patients were treated with…