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Efficacy of HIPEC After Laparoscopic Gastrectomy in Gastric Cancer

Laparoscopic gastrectomy plus hyperthermic intraperitoneal chemotherapy (HIPEC) improves outcomes for gastric cancer patients with positive peritoneal lavage cytology.

  • HIPEC-treated patients had significantly lower postoperative recurrence (66.7% vs. 90.9%) and visible metastasis (29.6% vs. 59.1%, p < 0.05).
  • 3-year overall survival for HIPEC patients was 51.8% versus 18.2% for non-HIPEC (p = 0.005).

Consider HIPEC for eligible patients to enhance survival and reduce recurrence rates.

  • Stage III cytology-negative patients had similar outcomes to HIPEC-treated patients (overall survival 56.4% vs. 51.8%, p = 0.39).

Journal Article by Lv C, Tong L (…) Cai L et 4 al. in Ann Surg Oncol

© 2025. Society of Surgical Oncology.

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Fluorescence Imaging with ICG Reduces Colorectal Leaks

Fluorescence imaging using indocyanine green significantly improves surgical outcomes in colorectal procedures.

  • It reduces anastomotic leak rates with an odds ratio of 0.58 (95% CI 0.44-0.75).
  • It enhances lymph node retrieval by an average of 6.32 nodes in gastrointestinal cancer surgeries (95% CI 4.43-8.22).

Intraoperative adjustments to transection points are feasible, improving surgical precision.

  • Evidence remains limited for other applications like thoracic duct identification and esophageal anastomoses.

Journal Article by Kapsampelis P, Calabrese EC (…) Keller DS et 15 al. in Surg Endosc

© 2025. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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Streamlined Robotic Training Cuts Time, Maintains Mastery

A refined robotic surgical training curriculum enhances skill acquisition while significantly lowering training time.

  • Mastery rates jumped from 83% to 100% with the new curriculum.
  • Mean console training time decreased from 7 hours to 5 hours and 42 minutes (p=0.005).

This efficient approach offers general surgery residents a more effective pathway to proficiency.

  • Median VR drill scores improved dramatically, with test scores up by over 400 points across both curricula.

Journal Article by Nunez-Rocha RE, Castillo-Flores S (…) Polanco PM et 7 al. in Surg Endosc

© 2025. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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New predictive models identify risks for liver tumor rupture

Understanding the risk factors for hepatocellular carcinoma (HCC) rupture can improve surgical outcomes.

  • Key risk factors include cirrhosis, protrusion ratio, and maximum tumor length.
  • The new capture nomogram achieved AUC values of 0.857, 0.824, and 0.840 across training, validation, and test groups, indicating high predictive accuracy.

Using these models can enhance early risk assessment and guide better management strategies for HCC patients, potentially reducing serious complications during surgery.

  • Random forest and deep learning models reached even higher AUCs of 0.870 and 0.872 in the test cohort.

Multicenter Study by Xia F, Liu Y (…) Zhu P et 30 al. in BJS Open

© The Author(s) 2025. Published by Oxford University Press on behalf of BJS Foundation Ltd.

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One-stage surgery beats two-stage for unresectable liver metastases.

  • Median overall survival was 46.5 months for one-stage versus 34.0 months for two-stage (p = 0.043).
  • Complication rates were similar: 11% for one-stage and 13% for two-stage (p = 0.567).
  • Local treatment was more successful with one-stage surgery, achieving complete resection or ablation in 52 patients compared to 29 in the two-stage group (p < 0.001).

Consider one-stage approaches as a first option for eligible patients, with two-stage surgery reserved for more complex cases.

Comparative Study by Bond MJG, Bolhuis K (…) Swijnenburg RJ et 23 al. in BJS Open

© The Author(s) 2025. Published by Oxford University Press on behalf of BJS Foundation Ltd.

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Laparoscopic Liver Resection in Segment 7 Shows Promise

Laparoscopic liver resection (LLR) for malignancies in segment 7 is a viable option, with potential short-term benefits.

  • LLR led to shorter hospital stays and a trend toward reduced blood loss compared to open liver resection (OLR).
  • Over 30 cases, the conversion rate to OLR decreased, indicating improved surgical safety with experience.

Surgeons can consider LLR as a safe alternative, especially as expertise builds, potentially enhancing patient outcomes.

Journal Article by Zhou H, Zheng H (…) Zhang W et 17 al. in Surg Endosc

© 2025. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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New Tool to Predict Parastomal Hernia Post-Colostomy

A newly developed nomogram predicts the risk of parastomal hernia in patients undergoing permanent colostomy for rectal cancer, crucial for improving patient outcomes.

  • In a study of 430 patients, 30.9% developed parastomal hernia.
  • Key risk factors include age ≥ 65 years (odds ratio 2.51) and BMI ≥ 25 kg/m² (odds ratio not specified).

This tool enables targeted management for high-risk patients, enhancing their quality of life.

  • The nomogram was validated internally through rigorous statistical methods.

Journal Article by Fu Y, Cheng Y (…) Wang D et 9 al. in Surg Endosc

© 2025. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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New CT Model Predicts Chemotherapy Response in Stomach Cancer

A dual-energy CT radiomics model can better predict neoadjuvant chemotherapy response in locally advanced gastric cancer, impacting surgical decision-making.

  • The dual-energy CT model achieved an AUC of 0.806 versus 0.729 with conventional CT in the training dataset (p = 0.041).
  • High-risk patients identified by the dual-energy CT model had nearly double the overall survival and disease-free survival risk compared to low-risk patients (HR = 1.996, p = 0.012; HR = 1.873, p = 0.037).

This model offers surgeons a reliable tool for selecting patients who may benefit most from treatment.

Journal Article by Li J, Lin X (…) Qu J et 6 al. in Eur J Surg Oncol

Copyright © 2025. Published by Elsevier Ltd.

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New Prognostic Tool for Acute Pancreatitis Outcomes

A novel Neutrophil-C-Reactive Protein Index (NCI) can enhance risk stratification for severe acute pancreatitis and in-hospital mortality, crucial in resource-limited settings.

  • Optimal NCI cut-off values are ≥1877 for severe pancreatitis and ≥3180 for mortality.
  • NCI predictions for severe pancreatitis had AUCs of 0.853 to 0.897 across different patient cohorts, outperforming other biomarkers.

This tool leverages common blood tests for timely and informed decision-making in surgical intervention.

  • For mortality, NCI AUCs ranged from 0.824 to 0.902, showing strong calibration and relevant post-test probabilities.

Journal Article by Huynh TM, Ong T (…) Quach DT et 2 al. in Int J Surg

Copyright © 2025 The Author(s). Published by Wolters Kluwer Health, Inc.

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Assessing Umbilical Fat Can Lower Incisional Hernia Risk

Umbilical fat is a critical factor in predicting incisional hernia risk after laparoscopic colorectal surgery.

  • Cumulative incidence of incisional hernia was 33.6%, with only 2.1% symptomatic cases.
  • Umbilical fat increased hernia risk significantly (hazard ratio 6.56).

Preoperative CT to evaluate umbilical fat can help identify high-risk patients.

  • Long surgical times and adjuvant chemotherapy also contribute to increased hernia risk.

Journal Article by Katayama C, Enokida Y (…) Saeki H et 8 al. in Surg Today

© 2025. The Author(s) under exclusive licence to Springer Nature Singapore Pte Ltd.

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