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Improved Survival in Gallbladder Cancer Post-Surgery

Textbook outcomes in liver surgery link directly to better survival in gallbladder cancer patients.

  • 61.9% of patients achieved textbook outcomes (TOLS) after curative-intent resection.
  • The 5-year overall survival rate was 45.4% in the TOLS group compared to 21.9% for non-TOLS (p < 0.001).

Surgeons should prioritize achieving TOLS to improve long-term patient outcomes.

  • Key risk factors for survival include total bilirubin >54 µmol/ml and poor differentiation, among others.

Journal Article by Li ZM, Ouyang HY (…) Qin T et 23 al. in Dig Surg

© 2025 S. Karger AG, Basel.

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Proactive Laparoscopic Cholecystectomy Safe for Complex Cases

Surgeons can confidently perform proactive emergency laparoscopic cholecystectomy for complex acute cholecystitis, showing strong outcomes even in high-risk patients.

  • Among 721 patients, the overall complication rate was just 6.9%, with severe complications at 1.2%.
  • Patients older than 80 had no higher complication rates (p = 0.14) compared to younger patients.
  • Indocyanine green cholangiography significantly reduced partial resection rates (0.7% vs. 6.3%, p = 0.005) and intraoperative blood loss.

This approach emphasizes safety in managing complex cases, supporting a shift towards proactive surgical intervention.

Journal Article by Liu Q, Han X (…) Zhao Y et 34 al. in Int J Surg

Copyright © 2025 The Author(s). Published by Wolters Kluwer Health, Inc.

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Biliary Stenting with Radioactive Seeds Enhances Survival in Cholangiocarcinoma

Combining biliary stenting with intraluminal 125 I seed brachytherapy significantly improves outcomes for advanced cholangiocarcinoma patients.

  • Patients receiving the combination treatment had a longer overall survival and better stent patency (p < 0.001) compared to those with stenting alone.
  • Complication rates were comparable between both groups, indicating safety (p > 0.85).

Integrating this technique could enhance surgical intervention effectiveness without compromising patient safety.

Systematic Review by Chen ML, Wang XL (…) Wang YB et 3 al. in Int J Surg

Copyright © 2025 The Author(s). Published by Wolters Kluwer Health, Inc.

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Effective TROPIS Procedure for High Complex Anal Fistulas

The TROPIS procedure shows promise for treating high complex anal fistulas with strong outcomes.

  • One-time cure rate stands at 80% with a final cure rate of 89%.
  • Recurrence rate after initial surgery is low at 20%, with no reported adverse events.

Consider adopting TROPIS as a viable option in surgical practice for this challenging condition.

  • Analysis included six studies with a total of 499 patients, confirming robust results without significant bias.

Meta-Analysis by Zhou P, Lu J, Sun Y and Wang J in Int J Surg

Copyright © 2025 The Author(s). Published by Wolters Kluwer Health, Inc.

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Surgical Strategies for Proximal Early Gastric Cancer: Dtr and Dft Shine

Surgeons need to know that proximal gastrectomy methods dtr and dft outperform tg and eg in key outcomes for early gastric cancer.

  • Reflux esophagitis rates were higher in eg compared to dft and dtr.
  • Anastomotic stenosis was less common with dtr than eg.
  • Dft achieved the highest 12-month hemoglobin levels; hospital stay was shorter compared to other methods.

Consider dtr and dft for improved patient outcomes and easier recovery in proximal early gastric cancer surgeries.

Meta-Analysis by Lee HJ, Kim JC (…) Yang HK et 6 al. in J Gastric Cancer

Copyright © 2025. Korean Gastric Cancer Association.

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Predict PHLF in HCC: New Nomogram Revolutionizes Surgery

A new nomogram predicts post-hepatectomy liver failure (PHLF) for hepatocellular carcinoma, improving patient outcomes.

  • Analyzed 654 patients, identifying 55 PHLF cases linked to seven key predictors: liver cirrhosis, total bilirubin, prothrombin time, albumin-bilirubin, fibrosis-4 index, ascites, and intraoperative blood loss.
  • Nomogram achieved an AUC of 0.880 for training and 0.879 for validation, indicating strong predictive accuracy.

Surgeons can now select patients with higher precision, reducing the risk of severe complications post-surgery.

Journal Article by Wang D, Ma Q (…) Zhang J et 4 al. in Front Med (Lausanne)

Copyright © 2025 Wang, Ma, Zhang, Hou, Zhang, Wu and Zhang.

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Effective Prehabilitation Reduces Complications in Colorectal Surgery

Multimodal prehabilitation significantly enhances outcomes for colorectal cancer patients undergoing surgery by lowering complications and improving recovery.

  • Multimodal prehabilitation cut postoperative complications by 53% (odds ratio: 0.47).
  • It also shortened hospital stays by an average of 1.17 days.

This integrated approach improves physical function, shown by a 27-meter increase in the 6-minute walk test pre-surgery, and reduces anxiety scores.

  • Benefits last with a 19-meter improvement sustained 4 weeks post-surgery.

Systematic Review by Li N, Liu X (…) Xie X et 2 al. in Front Med (Lausanne)

Copyright © 2025 Li, Liu, Wang, Song and Xie.

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Improved Survival Rates for Surgical Gastric Cancer Patients

Conditional relative survival after gastric cancer surgery shows promising results, suggesting better outcomes than previously thought.

  • Five-year conditional relative survival (CRS) rose from 87.2% at one year to 95.4% at five years post-surgery.
  • Stage III patients saw significant improvement, with CRS increasing from 53.2% at one year to 85.2% at five years.

Surgery remains a viable option for older patients, with those over 80 showing high survival rates similar to younger cohorts.

  • Total gastrectomy patients may require additional nutritional support due to lower CRS compared to distal gastrectomy.

Journal Article by Park H, Cho YS (…) Shin A et 5 al. in J Gastric Cancer

Copyright © 2025. Korean Gastric Cancer Association.

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Predicting Postoperative Leakage in Gastrectomy with AI

This study shows that deep learning can predict leakage during laparoscopic gastrectomy for gastric cancer, improving surgical outcomes.

  • Leakage rates were 1.3% at the duodenal stump and 4.3% at the esophagojejunal anastomoses.
  • The ResNet18 model achieved a recall of 84.7% for stump leakage and 80% for anastomosis leakage when trained on high-quality, single-image datasets with augmentation.

Using AI during surgery could facilitate timely interventions, enhancing patient safety and outcomes.

  • Key image features, both local and surrounding tissues, were critical for accurate predictions.

Journal Article by Park KB, Lee H (…) Seo H et 6 al. in J Gastric Cancer

Copyright © 2025. Korean Gastric Cancer Association.

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Structured Robotic Surgery Training Improves Outcomes in Cancer Patients

A structured training program significantly enhances surgical performance for robotic procedures.

  • 16 experienced surgeons trained in a four-stage curriculum, with only 8 achieving full certification.
  • Robotic procedures resulted in less blood loss (266.2 ml vs. 598.2 ml) despite longer operative times (304.9 min vs. 259.1 min).
  • No difference in lymph node yield or complication rates compared to traditional methods.

This model can be adapted for other institutions, ensuring safer transitions to robotic techniques in public health settings.

Randomized Controlled Trial by Abdalla RZ, Nahas WC, Cecconello I and Ribeiro U in J Robot Surg

© 2025. The Author(s), under exclusive licence to Springer-Verlag London Ltd., part of Springer Nature.

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