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Prophylactic clipping demonstrates cost savings for colon polyp procedures

A comprehensive analysis of 4,557 patients revealed that prophylactic clipping after endoscopic mucosal resection for large non-pedunculated colon polyps resulted in significant cost savings. Specifically, in a typical case, clipping yielded an incremental cost-effectiveness ratio (ICER) of -$154,706. This technique proved cost-effective for large polyps and beneficial for patients on antithrombotic therapy when utilizing up to two clips. Optimizing costs and clip usage can enhance the economic feasibility of the approach.

Journal Article by Sonaiya S, Patel R (…) Mohan BP et 7 al. in Gastrointest Endosc

Copyright © 2025 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.

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SSI prevention bundle significantly reduces infection rates in surgery

A multifaceted surgical site infection (SSI) prevention bundle effectively decreased infection rates in patients undergoing emergency general surgery (EGS). The study reported significant reductions of 48% for superficial infections, 68% for deep infections, and 55% for intra-abdominal infections. Additionally, the median hospital stay shortened from 13 to 8 days with the bundle implementation, despite a longer operative time. These outcomes suggest that adopting bundled strategies can enhance surgical care in emergency settings.

Journal Article by Isand KG, Saar S (…) Talving P et 5 al. in World J Surg

© 2025 International Society of Surgery/Société Internationale de Chirurgie (ISS/SIC).

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TEP repairs present higher reoperation risks for men

Findings indicate that while reoperation rates for groin hernia repair are generally low, those who underwent totally extraperitoneal (TEP) repairs had a significantly higher risk of recurrence compared to transabdominal preperitoneal (TAPP) and Lichtenstein techniques in males. Specifically, TEP was associated with increased reoperation hazards (HR 1.38 vs. TAPP; HR 1.44 vs. Lichtenstein). Conversely, in females, TAPP and TEP showed lower reoperation risks than Lichtenstein, underscoring the need for optimized hernia repair strategies informed by international comparisons.

Observational Study by Andresen K, Kroon L (…) de la Croix H et 4 al. in Hernia

© 2025. The Author(s).

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EUS-FNA/B proves effective for rectal and perirectal lesions

Endoscopic ultrasound-guided fine-needle aspiration and biopsy (EUS-FNA/B) was found effective in diagnosing rectal and perirectal lesions in 79.2% of cases. Of 77 patients studied, EUS-FNA/B provided conclusive diagnoses, enabling timely treatment decisions—confirming malignancies in 32 patients and preventing unnecessary procedures in 14. A definitive diagnosis of a gastrointestinal stromal tumor facilitated neoadjuvant chemotherapy and subsequent surgery. Despite some adverse events, EUS-FNA/B demonstrated a strong safety profile and clinical utility for this patient group.

Journal Article by Bae JH, Park JB (…) Byeon JS et 8 al. in J Dig Dis

© 2025 Chinese Medical Association Shanghai Branch, Chinese Society of Gastroenterology, Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine and John Wiley & Sons Australia, Ltd.

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Non-invasive CT-based model predicts tumor immune environment in CRC

A deep learning radiomics model utilizing preoperative CT scans shows promise for non-invasively predicting the tumor immune microenvironment (TIME) in colorectal cancer patients. The Densenet-169 model achieved an AUC of 0.892 for tumor-stroma ratio (TSR), while the Densenet-121 model reached AUCs of 0.851 for tumor-infiltrating lymphocytes and 0.852 for immune score. These models could facilitate personalized immunotherapy strategies, significantly enhancing CRC management.

Journal Article by Zhou C, Zhang YF (…) Da MX et 2 al. in World J Gastrointest Oncol

©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.

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Enhanced recovery after surgery improves cancer survival rates

A multicenter trial involving 527 gastric cancer patients found that those receiving enhanced recovery after surgery (ERAS) showed significantly better three-year overall survival (86.56% vs. 80.11%) and disease-free survival (79.57% vs. 69.57%) compared to conventional care. The ERAS group experienced fewer complications, shorter hospital stays, and lower medical expenses. Notably, patients with stage III cancer benefited the most from ERAS, showcasing its potential to enhance oncological outcomes in laparoscopic distal gastrectomy.

Comparative Study by Tian Y, Cao S (…) Zhou Y et 19 al. in Ann Surg

Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.

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Early VTE prophylaxis significantly reduces complications in trauma patients

Initiating pharmacologic VTE prophylaxis within 24 hours of major trauma reduces the risk of venous thromboembolism (VTE) by 42% compared to later initiation. In a study comparing 3,369 early initiation patients with 3,200 late initiators, VTE incidence was 2.8% versus 7.8%, respectively. Additionally, early initiation correlated with lower intracranial hemorrhage and mortality rates. These findings suggest that timely VTE prophylaxis should be adopted as standard care, including in those with traumatic brain injuries.

Journal Article by Kerwin AJ, Byerly S (…) Knudson MM et 4 al. in Ann Surg

Copyright © 2025 Wolters Kluwer Health, Inc. All rights reserved.

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Acute Pain Services Outperform Traditional Models in Postoperative Care

A network meta-analysis of 38 randomized controlled trials reveals that acute pain services (APS) significantly alleviate postoperative pain compared to traditional doctor-nurse models. Nurse-based anesthesiologist specialist-supervised APS (NBASS-APS) achieved the highest effectiveness, with a 98% probability of optimal pain relief, followed by nurse-based anesthesiologist-supervised APS, multidisciplinary teams, and conventional models. These findings underscore the importance of specialized pain management strategies to enhance recovery and quality of life for adults post-surgery.

Meta-Analysis by Chen L, Feng X (…) Zhu T et 5 al. in Int J Surg

Copyright © 2025 The Author(s). Published by Wolters Kluwer Health, Inc.

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ARMS offers fewer complications than TIF for GERD treatment

A comparative analysis reveals ARMS as a preferable option for treating gastroesophageal reflux disease (GERD) due to shorter procedure times and reduced complications, specifically dysphagia and bleeding. While TIF shows higher rates of recurrence and reoperation, it offers better long-term efficacy in medication reduction and quality-of-life improvements, particularly in previously untreated patients. Individual treatment choices should be tailored based on patient-specific factors, underscoring the importance of personalized approaches in GERD management.

Review by Mohan A, Sohail F (…) Kumar V et 6 al. in Ann Med Surg (Lond)

Copyright © 2025 The Author(s). Published by Wolters Kluwer Health, Inc.

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Postsurgical endoscopy is essential for optimal GI surgery outcomes

Postsurgical endoscopy emerges as a vital diagnostic tool in gastrointestinal surgery. It significantly aids in early complication detection, healing assessment, symptom management, and monitoring for cancer recurrence. As endoscopic techniques advance, their integration into clinical practice and surgical training is crucial for improving postoperative care. This review not only highlights the advancements in endoscopic technologies but also emphasizes real-life applications that showcase its indispensable role in enhancing surgical outcomes for patients.

Review by Kamaleddine I, Popova M, Alwali A and Schafmayer C in Visc Med

© 2025 S. Karger AG, Basel.

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