Blog

Nomogram effectively predicts severe complications post-surgery after COVID-19

A novel nomogram crafted to forecast severe postoperative complications in elective hepato-pancreato-biliary surgery following COVID-19 breakthrough infections demonstrated high accuracy. The model utilized data from 2,636 patients and identified significant predictors, including timing of surgery relative to the infection and vaccination status. With an area under the curve (AUC) ranging from 0.841 to 0.919 across cohorts, this tool can assist clinicians in better risk stratification and decision-making for vulnerable surgical patients.

Journal Article by Yang Y, Dang Z (…) Zhou WP et 6 al. in Hepatobiliary Pancreat Dis Int

Copyright © 2024 First Affiliated Hospital, Zhejiang University School of Medicine in China. Published by Elsevier B.V. All rights reserved.

read the whole article in Hepatobiliary Pancreat Dis Int

open it in PubMed

Dexmedetomidine significantly reduces surgical stress response markers.

Administration of dexmedetomidine before surgery markedly lowered serum levels of stress-related biomarkers in patients undergoing ENT procedures. A study involving 100 patients revealed that those receiving dexmedetomidine experienced significant reductions in cortisol, TNF-α, and interleukin-6 levels compared to a control group, with values dropping from 139.73 to 10.18, 99.51 to 0.96, and 85.09 to 0.96, respectively. The intervention also contributed to smoother recovery without nausea or vomiting.

Journal Article by Ajmal K, Waheed A, Farooqi R and Mansoor Q in Pak J Med Sci

Copyright: © Pakistan Journal of Medical Sciences.

read the whole article in Pak J Med Sci

open it in PubMed

Laparoscopic hepatectomy shows safety and effectiveness for liver cancer

Laparoscopic hepatectomy (LH) emerges as a safe, effective treatment for primary hepatocellular carcinoma (HCC) in favorable locations, as seen in a study involving 159 patients. While LH and open hepatectomy (OH) showed no significant differences in major complications or 90-day mortality, LH reduced transfusion rates, hospital stays, and readmission rates. Importantly, long-term survival outcomes remained comparable between both approaches, highlighting LH’s advantages during its development phase.

Journal Article by Lee YH, Huang YT (…) Chen YC et 2 al. in Tzu Chi Med J

Copyright: © 2024 Tzu Chi Medical Journal.

read the whole article in Tzu Chi Med J

open it in PubMed

Super-oxidized solution reduces surgical-site infections in appendicitis

In a randomized clinical trial involving 102 patients with perforated appendicitis, peritoneal and wound lavage with super-oxidized solution significantly lowered surgical-site infections compared to normal saline. The results showed a reduction in overall infections from 37.2% to 15.6% and superficial infections from 35.3% to 9.8%. With a number-needed-to-treat of four, the findings suggest this intervention is beneficial in surgical settings, with no adverse events reported.

Multicenter Study by Sellappan H, Alagoo D (…) Chuah JA et 3 al. in BJS Open

© The Author(s) 2024. Published by Oxford University Press on behalf of BJS Foundation Ltd.

read the whole article in BJS Open

open it in PubMed

Robotic surgery is feasible for acute care surgeons.

Findings indicate that robotic surgery can be safely integrated into acute care surgery practices. An analysis of 200 procedures revealed that common operations included cholecystectomies and hernia repairs, achieving comparable hospital lengths of stay to laparoscopic methods. Notably, only two operations required a conversion to open surgery. These results suggest that robotic techniques could enhance surgical practice, with further studies planned for multi-center trials comparing robotic and traditional laparoscopic surgeries.

Journal Article by Sanderfer VC, Jensen S (…) Ross SW et 10 al. in Surg Endosc

© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

read the whole article in Surg Endosc

open it in PubMed

5-Hydroxyindoleacetic acid levels distinguish perforated from nonperforated appendicitis

5-hydroxyindoleacetic acid (5-HIAA) levels in urine significantly differed between patients with perforated and non-perforated appendicitis, indicating its potential as a diagnostic biomarker. Specifically, 5-HIAA was higher in the perforated group (0.5 mg/dl) compared to the non-perforated group (0.3 mg/dl), and the study reported a diagnostic accuracy of 88%, with sensitivity at 82%. These findings suggest that measuring 5-HIAA may enhance the timely diagnosis of acute appendicitis complications.

Journal Article by Mohammadi Tofigh A, Samsami M (…) Adinevand E et 4 al. in BMC Gastroenterol

© 2024. The Author(s).

read the whole article in BMC Gastroenterol

open it in PubMed

Understanding jejunal vein anatomy improves surgical outcomes in pancreatoduodenectomy

A systematic review and meta-analysis of 14 studies involving 1,888 patients revealed key anatomical insights into jejunal veins during pancreaticoduodenectomy. The findings indicate that 79.6% of cases exhibit a posterior course of the first jejunal vein (FJV) and jejunal trunk (FJT), while 20.4% show an anterior course. Preoperative radiological assessment of these variations potentially enhances surgical strategy and accuracy, thereby reducing the risk of bleeding during procedures involving the pancreatic head.

Systematic Review by Cirocchi R, Matteucci M (…) Tebala GD et 6 al. in Dig Surg

S. Karger AG, Basel.

read the whole article in Dig Surg

open it in PubMed

Network analysis identifies more accurate emergency surgery care regions

A comparison of community detection methods found that modularity optimization (MO) significantly outperforms Dartmouth Health Referral Regions (HRRs) in delineating emergency general surgery (EGS) networks. An analysis of 1,244,868 patient encounters in New York and California revealed that MO identified fewer but more geographically accurate regional networks, with substantial reclassification of hospitals between communities. These findings suggest that network science methods can enhance the coordination of regional care systems for EGS patients.

Journal Article by Han J, Wan N, Horns JJ and McCrum ML in JAMA Netw Open

read the whole article in JAMA Netw Open

open it in PubMed

Sigmoid-type achalasia shows higher risk of esophageal cancer

In a study involving 450 achalasia patients undergoing peroral endoscopic myotomy (POEM), treatment outcomes were favorable across disease types, with efficacy rates of 97.9% and 94.2% at one and two years, respectively. However, the incidence of esophageal cancer varied significantly among types: 1% in straight, 2.5% in sigmoid type 1, and 10% in sigmoid type 2. Notably, there was a statistically significant trend indicating increased cancer risk with more advanced achalasia stages.

Journal Article by Shiwaku A, Shiwaku H (…) Hasegawa S et 2 al. in Dig Endosc

© 2024 Japan Gastroenterological Endoscopy Society.

read the whole article in Dig Endosc

open it in PubMed

Psychiatric disorders increase complications after IBD surgery

In a study of 81,955 patients undergoing surgery for inflammatory bowel disease (IBD), 26.6% were identified with psychiatric disorders (PDs). These patients faced significantly higher risks of postoperative ileus, longer hospital stays, and increased costs. Furthermore, they had higher odds of non-home discharge and 30-day readmissions. The prevalence of PDs among IBD patients rose from 24.3% to 28.5% during the study period, indicating an urgent need for preoperative psychiatric care to improve surgical outcomes.

Journal Article by Ng AP, Porter G (…) Lee H et 4 al. in J Gastrointest Surg

Copyright © 2024. Published by Elsevier Inc.

read the whole article in J Gastrointest Surg

open it in PubMed