Blog

Gastrin Orchestrates Glucose Regulation Post-Sleeve Gastrectomy

Gastrin plays a central role in glucose improvement after sleeve gastrectomy (SG). SG induces a medium-term elevation of the insulin response and plasma gastrin levels, with long-term depletion of the insulin response and elevated oral glucose tolerance test results. Gastrin antagonists, like netazepide, prevent these effects. This study highlights the dual effects of gastrin on insulin release and beta-cell mass post-SG.

Journal Article by Pérez-Arana GM, Almorza-Gomar D (…) Prada-Oliveira JA et 7 al. in J Gastrointest Surg

Copyright © 2024 Society for Surgery of the Alimentary Tract. Published by Elsevier Inc. All rights reserved.

read the whole article in J Gastrointest Surg

open it in PubMed

Impact of Radiologic Splenic Vessels Involvement on Outcomes after Distal Pancreatectomy for Pancreatic Adenocarcinoma

Study evaluates how radiologic splenic vessels involvement affects postoperative complications, overall survival, and disease-free survival in pancreatic adenocarcinoma patients undergoing distal pancreatectomy. Findings suggest that radiologic splenic vessels involvement increases major complication rates and decreases survival outcomes, serving as a potential prognostic marker for treatment decisions in these patients.

Journal Article by Blanco-Fernández G, Serradilla-Martín M (…) Ramia JM et 17 al. in J Gastrointest Surg

Copyright © 2024 Society for Surgery of the Alimentary Tract. Published by Elsevier Inc. All rights reserved.

read the whole article in J Gastrointest Surg

open it in PubMed

Impact of COVID-19 Pandemic on Operative Trends for Pancreatic and Hepatic Malignancies

The study found that while operations for pancreatic malignancies remained stable during the pandemic, operations for hepatic malignancies were temporarily reduced but quickly returned to normal levels. Additionally, there was an increase in pancreatic operations following neoadjuvant therapy. These results suggest that surgery for hepato-pancreato-biliary malignancies was prioritized during the COVID-19 pandemic.

Journal Article by Manzella A, Ecker BL (…) Pitt HA et 8 al. in BMC Surg

Copyright © 2024 Elsevier Inc. All rights reserved.

read the whole article in BMC Surg

open it in PubMed

Survival Discrepancies in Colon Cancer Staging

Survival paradox persists between stage IIB/C and IIIA colon cancer, even after adjusting for chemotherapy and lymph node retrieval. Optimal treatment for IIIA yields significantly better 5-year survival rates compared to IIB/C. Stage remains an independent predictor of overall survival, with significant differences in survival outcomes between different sub-stages. The TNM system should consider revising to address this discrepancy.

Journal Article by Chu QD, Li T (…) Wu XC et 6 al. in Surg Endosc

© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

read the whole article in Surg Endosc

open it in PubMed

Impact of Preoperative Comorbidities on %EBWL After Bariatric Surgery

Patients with higher baseline BMI, diabetes mellitus, hypothyroidism, and those undergoing laparoscopic sleeve gastrectomy may experience lower %EBWL in the first year post-bariatric surgery. Anxiety, depression, and obstructive sleep apnea were not significantly associated with %EBWL. This study highlights the need for tighter control of certain comorbidities to optimize weight loss outcomes after bariatric surgery.

Journal Article by Remmel S, Noom M (…) DuCoin CG et 5 al. in Surg Endosc

© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

read the whole article in Surg Endosc

open it in PubMed

Laparoscopic Gastrectomy in Super-Geriatric Gastric Cancer

Geriatric patients with locally advanced gastric cancer who underwent laparoscopic gastrectomy had lower overall complication rates, shorter hospital stays, and less blood loss compared to those who underwent open gastrectomy. There was no significant difference in 3-year overall survival between the two groups, suggesting laparoscopic gastrectomy may offer similar or better surgical and oncological outcomes for super-geriatric patients.

Journal Article by Tian Z, Xia M (…) Wang D et 5 al. in Surg Endosc

© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

read the whole article in Surg Endosc

open it in PubMed

Quality Assessment of Laparoscopic Sleeve Gastrectomy Videos: Academic vs. Online Comparison

Academic laparoscopic sleeve gastrectomy videos provide more detailed information on technical steps, instruments used, and patient outcomes compared to online videos. A newly developed quality assessment tool can enhance the value and reliability of educational video resources. Commercial videos on platforms like YouTube score lower in quality reporting, highlighting the importance of peer-reviewed publications in surgical video dissemination.

Review by Alghazawi L, Fadel MG (…) Fehervari M et 7 al. in Obes Surg

© 2024. Crown.

read the whole article in Obes Surg

open it in PubMed

Adaptation and Validation of the Brazilian Version of the Yale Food Addiction Scale for Severe Obesity

A study validated the Brazilian version of the Yale Food Addiction Scale (BR-YFAS 2.0-OBES) for individuals with severe obesity, demonstrating its adequacy in terms of convergent validity, reliability, and one-factor structure. This adaptation allows its use among Brazilian candidates for bariatric surgery and individuals with BMI ≥ 30 kg/m², facilitating assessment of food addiction in this population.

Journal Article by Marcon ER, Brillmann M (…) Oliveira MS et 5 al. in Obes Surg

© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

read the whole article in Obes Surg

open it in PubMed

Outpatient Management and Antibiotic Use in Acute Diverticulitis

Outpatient observation for acute diverticulitis (Hinchey 1a) and no antibiotics resulted in lower recurrence rates and shorter hospital stays compared to inpatient treatment and antibiotics. Recurrence, hospital admissions, and mortality rates were similar between outpatient and inpatient management. Future studies are needed to confirm the effectiveness of observation-only and antibiotics-free approaches in managing uncomplicated acute diverticulitis.

Journal Article by Mohamedahmed AY, Zaman S (…) Husain N et 5 al. in Int J Colorectal Dis

© 2024. The Author(s).

read the whole article in Int J Colorectal Dis

open it in PubMed

Impact of Routine Lymph Node Dissection on Intrahepatic Cholangiocarcinoma Patients

Therapeutic effects of routine lymph node dissection (LND) with liver resection for intrahepatic cholangiocarcinoma (ICC) were inconclusive. However, subgroup analyses revealed a potential benefit for ICC patients with low risk of bias, suggesting a positive impact on overall survival. More studies are needed to clarify the role of LND in this patient population.

Review by Ishii T, Iwaki K (…) Hatano E et 3 al. in HPB (Oxford)

Copyright © 2024 International Hepato-Pancreato-Biliary Association Inc. Published by Elsevier Ltd. All rights reserved.

read the whole article in HPB (Oxford)

open it in PubMed