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Mesenteric Lymph Nodes Not Linked to Ovarian Cancer Survival

Researchers examined the role of mesenteric lymph nodes (MLNs) in digestive resection for advanced ovarian cancer (OC) with peritoneal metastases. Out of 159 patients, 77 underwent digestive resection, with 61.1% having MLNs examined, and 56.8% showed involvement. Surprisingly, MLN status didn’t significantly impact overall survival or progression-free survival. This calls for further systematic and standardized studies to verify these results, highlighting the need for more research on the subject.

Journal Article by Channawi A, Pop FC (…) Liberale G et 5 al. in Ann Surg Oncol

© 2023. The Author(s).

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Repeat Cytoreduction and HIPEC Boost Survival in Recurrent Appendiceal Adenocarcinoma

When dealing with recurring mucinous appendiceal adenocarcinoma, undergoing repeat cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) can be a game-changer. This study from MD Anderson Cancer Center reveals that patients who opt for repeat CRS/HIPEC enjoy similar recurrence-free survival compared to those initially treated, and even better overall survival than patients relying solely on systemic chemotherapy. These findings emphasize the potential benefits of this treatment strategy, especially when administered by experienced teams in high-volume centers.

Journal Article by Bhutiani N, Grotz TE (…) Fournier KF et 12 al. in Ann Surg Oncol

© 2023. The Author(s).

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Sarcopenia Development During Neoadjuvant Therapy Spells Trouble for Esophageal Adenocarcinoma Patients

This study explored how sarcopenia, muscle loss often seen in cancer patients, impacts outcomes for esophageal adenocarcinoma patients undergoing neoadjuvant therapy. Among 71 patients, those who developed sarcopenia before surgery had significantly worse overall survival compared to those who were sarcopenic at diagnosis or experienced no change in muscle status. The cause of death in many cases was not cancer-related. Developing sarcopenia during neoadjuvant therapy could be a negative predictor of overall survival in patients requiring esophagogastrectomy.

Journal Article by Pierce K, Philips P (…) Martin RC et 2 al. in BMC Surg

Copyright © 2023 Elsevier Inc. All rights reserved.

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Women Fare Better in Surgical Outcomes for Inflammatory Bowel Disease

In this study, researchers delved into surgical outcomes for inflammatory bowel disease patients based on their sex. Analyzing data from over 3,000 patients, they discovered that women had lower odds of serious adverse events compared to men. This difference was particularly notable in patients with ulcerative colitis, where women had a 54% lower risk of serious adverse events compared to men. These findings offer valuable insights for tailoring surgical planning and perioperative care in a patient-centered manner.

Journal Article by Sundel MH, Newland JJ (…) Bafford AC et 3 al. in Dis Colon Rectum

Copyright © The ASCRS 2023.

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Innovative Imaging Technique Shows Promise for Assessing Organ Perfusion During Laparoscopic Surgery

This groundbreaking study introduces Imaging Photoplethysmography (IPPg) as a new method for quantitatively evaluating organ perfusion during laparoscopic surgeries. In clinical settings, researchers successfully used a laparoscope connected to a digital monochrome camera, along with green light illumination, to assess organ perfusion in cancer patients. They found that IPPg could visualize and quantify perfusion gradients in organs before and after resection, even during physiological tests. This innovative technique shows great potential for intra-abdominal perfusion assessment during minimally invasive surgeries.

Journal Article by Kashchenko VA, Lodygin AV (…) Kamshilin AA et 2 al. in Surg Endosc

© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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Robotic Hepatectomy Shows Promise in Treating Malignant Liver Diseases

This groundbreaking study analyzed the outcomes of robotic hepatectomy for five major malignant liver diseases. Among the 210 patients who underwent this procedure, including cases like colorectal liver metastases and hepatocellular carcinoma, the results were promising. A favorable 5-year overall survival benefit was observed across these disease processes. The robotic platform demonstrated its prowess in enabling precise surgical dissection for complex hepatobiliary surgeries, leading to high rates of successful resections and excellent clinical outcomes.

Journal Article by Dugan MM, Sucandy I (…) Rosemurgy A et 4 al. in Am J Surg

Copyright © 2023 Elsevier Inc. All rights reserved.

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EUS-Guided Radiofrequency Ablation: A Safe and Effective Alternative for Left Adrenal Tumors

Researchers conducted a study at Asan Medical Center to assess the feasibility, effectiveness, and safety of EUS-guided radiofrequency ablation (EUS-RFA) for treating left adrenal tumors. The results were promising, with a 100% technical success rate in performing EUS-RFA. Most patients (73%) achieved a complete response after a median of 2 EUS-RFA sessions. Importantly, no moderate or severe adverse events were reported, indicating that EUS-RFA is a safe and effective alternative to surgery for patients at high surgical risk with left adrenal tumors.

Journal Article by Cho SH, Kim DH (…) Lee SK et 4 al. in Gastrointest Endosc

Copyright © 2023 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.

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EUS-Guided Gallbladder Drainage Safer Than Percutaneous Cholecystostomy in High-Risk Patients

In high-risk surgical patients with acute cholecystitis, a systematic review and meta-analysis compared two alternative treatments: endoscopic ultrasound-guided gallbladder drainage using lumen-apposing metal stents (EUS-GBD-LAMS) and percutaneous cholecystostomy (PTGBD). The study found that while the two groups had similar early adverse events, EUS-GBD-LAMS was associated with significantly lower rates of delayed and overall adverse events. Additionally, patients undergoing EUS-GBD-LAMS had shorter hospital stays compared to PTGBD, making it a safer and more efficient option for non-surgical candidates with acute cholecystitis.

Journal Article by Hayat U, Al Shabeeb R (…) Adler DG et 7 al. in Gastrointest Endosc

Copyright © 2023 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.

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Conflict of Interest Disclosures Fall Short in Robotic Surgery Studies

A study scrutinized conflict of interest (COI) disclosures in gastrointestinal and abdominal wall surgery research related to robotics. It found that a substantial majority (86.4%) of these studies had inaccurate or undisclosed COI statements. Moreover, many authors who received funding from robotics companies failed to report it in their disclosures. These findings emphasize the need for improved COI definitions and standardized reporting processes in the field. Accurate disclosure statements are vital to maintaining research integrity and transparency.

Journal Article by Jafar U, Usama M (…) Aziz H et 4 al. in J Am Coll Surg

Copyright © 2023 by the American College of Surgeons. Published by Wolters Kluwer Health, Inc. All rights reserved.

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Laparoscopic Pancreaticoduodenectomy Holds Its Own in Short-Term Outcomes for Pancreatic Ductal Adenocarcinoma

In a randomized clinical trial, researchers compared laparoscopic and open pancreaticoduodenectomy for patients with pancreatic ductal adenocarcinoma. The study found that, despite longer operative times, laparoscopic procedures led to less blood loss. Both groups had similar 90-day mortality, rates of complications, and postoperative length of stay. The results suggest that laparoscopic pancreaticoduodenectomy, when performed by experienced surgeons in specialized institutions, yields comparable short-term outcomes to open surgery for patients with pancreatic ductal adenocarcinoma.

Journal Article by Wang M, Pan S (…) Qin R et 28 al. in JAMA Surg

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