Monitoring end-tidal carbon dioxide (etCO2) during pancreaticoduodenectomy can guide surgical decisions and improve patient outcomes in pancreatic ductal adenocarcinoma (PDAC).

• Low and high etCO2 levels are linked to worse overall survival compared to normal levels (p < 0.05).
• Cox regression shows low etCO2 has a hazard ratio of 1.80 and high etCO2 a ratio of 1.65 for disease-free survival, indicating significant risk factors.

This underscores the importance of etCO2 monitoring for risk stratification in PDAC surgeries.

• The study evaluated 243 patients with a median age of 68.5 years.

Colloid carcinoma (cc) is a rare but distinct subtype of pancreatic cancer, revealing favorable outcomes compared to tubular carcinoma (tc).

• CC accounts for 25% of invasive intraductal papillary mucinous neoplasms.
• Patients with cc were more often male (70%), and had a higher prevalence of steatorrhea (26%) and diabetes (44%).
• Median overall survival for cc is significantly longer at 69 months compared to 31 months for tc.

Surgeons should recognize cc’s unique features to improve prognostic assessments and personalize management strategies.

3D-guided planning significantly enhances laparoscopic hepatectomy for complex liver tumors.

• Reduced intraoperative blood loss: 80 ml vs. 160 ml (p < 0.001).
• Lower bile leakage rate: 3.1% vs. 15.4% (p = 0.015) in matched pairs.

Consider adopting 3D-assisted techniques for better outcomes in challenging cases.

• In special-segment cases, operative times were shorter: 180 min vs. 250 min (p < 0.001) with 3D guidance.
• Bile leakage in special segments also decreased: 9.5% vs. 42.9% (p = 0.014).