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Plastic and Metal Stents Show No Survival Difference in Pancreatic Cancer

Stent choice for preoperative biliary drainage in pancreatic cancer does not affect long-term survival.

  • Among 6,429 patients, overall and recurrence-free survival were similar for plastic (PS) and metal stents (MS) after pancreaticoduodenectomy, even in those receiving neoadjuvant therapy.
  • No significant difference in postoperative complications between PS and MS.

Choose stents based on drainage duration and treatment approach, not survival expectations.

  • Secondary analysis showed no survival differences between endoscopic retrograde cholangiopancreatography (ERCP) and percutaneous transhepatic biliary drainage (PTBD).

Journal Article by Nagai K, Hirakawa S (…) Masamune A et 15 al. in Gastrointest Endosc

Copyright © 2026. Published by Elsevier Inc.

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Prehabilitation Shows Promise in Abdominal Cancer Surgery

Multimodal prehabilitation may enhance baseline immune function in patients before abdominal cancer surgery, but its effect on postoperative immune outcomes appears limited.

  • In a study of 130 patients (102 prehabilitation, 28 control), prehabilitation reduced pro-inflammatory cytokines and increased IL-10 levels.
  • No significant immune function differences were noted on postoperative day 1 between groups.

This suggests prehabilitation might optimize pre-surgical readiness, but benefits for postoperative immune response may not be substantial.

Journal Article by Jacobs LMC, Drager LD (…) Warlé MC et 6 al. in Br J Surg

© The Author(s) 2026. Published by Oxford University Press on behalf of BJS Foundation Ltd.

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Addressing the Psychological Impact of Surgical Errors

Surgeons must prioritize mental health after adverse events to improve practice and patient care.

  • Up to 96% of surgical staff feel emotional distress post-error, with guilt (53-89%) and anxiety (45-88%) prevalent.
  • Disclosure rates for surgical errors range from 17% to 62%, hindered by fear of litigation and unclear protocols.

Enhancing organizational strategies for disclosure and psychological support is critical for clinician well-being.

  • Training interventions can improve communication, but significant gaps in support and training persist.

Review by Busch IM, Marinelli V (…) Rimondini M et 7 al. in Ann Surg Oncol

© 2026. Society of Surgical Oncology.

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EndoBarrier Shows Promise for Type 2 Diabetes in Obesity

Endoscopic duodenal-jejunal bypass liner may significantly improve glycemic control and weight loss in patients with poorly controlled type 2 diabetes and obesity.

  • At one year, HbA1c levels dropped by 1.10% in the DJBL group, compared to just 0.28% in the sham group (p=0.0004).
  • Patients with HbA1c ≤ 7% more than tripled in the DJBL group (28.3% vs. 9.4%, p=0.0003).

Consider DJBL for selected patients as it may enhance weight loss and glycemic outcomes.

  • Device-related serious adverse event rate was 9.4%, with specific concerns being intolerance (3.7%) and hemorrhage (2.8%).

Journal Article by Thompson CC, Jirapinyo P (…) Schauer P et 11 al. in Ann Surg

Copyright © 2025 Wolters Kluwer Health, Inc. All rights reserved.

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Transplant Centers Reduce Mortality in Emergency Surgery for Kidney Patients

Treating kidney transplant patients at specialized centers improves outcomes in emergency surgeries.

  • 30-day mortality was significantly higher at academic centers compared to transplant centers (aOR: 3.52).
  • 31% of patients experienced complications or mortality overall, emphasizing the risks involved.

Emergency general surgical care for transplant patients should prioritize transplant centers to enhance survival and minimize complications.

Journal Article by Nantais J, Saskin R (…) Baxter NN et 3 al. in Ann Surg

Copyright © 2026 Wolters Kluwer Health, Inc. All rights reserved.

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New Peptide Strategy Outperforms Balloon for Post-ERCP Bleeding

A self-assembling peptide-first approach significantly enhances hemostasis for immediate post-sphincterotomy bleeding during ERCP.

  • Successful initial hemostasis was achieved in 92.3% of the peptide group versus 76.9% in the balloon group (15.4% risk difference, p=0.027).
  • The mean procedure time was shorter for the peptide strategy, and rescue devices were needed less often (7.7% vs 23.1%, p=0.033).

Consider using the peptide strategy as a first-line option, pending further validation.

Journal Article by Ogura T, Ikeura T (…) Hakoda A et 17 al. in Gastrointest Endosc

Copyright © 2026 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.

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Rectus Sheath Catheters Offer Safe Pain Relief for Surgery

Rectus sheath catheters provide effective pain management after open surgery while reducing complications and costs compared to thoracic epidural analgesia.

  • No significant difference in postoperative pain or opioid use between rectus sheath catheters and epidurals.
  • Rectus sheath catheters cut hypotension risk by 60% (risk ratio 0.40) and can save $500 to $6,632 per case.

These findings support rectus sheath catheters as a viable option for efficient pain management, especially in fast-track surgery settings.

  • Subgroup analysis shows benefits in urinary retention and mobilization time with rectus sheath catheters in non-visceral surgeries.

Journal Article by Fankhauser CD, Breitenstein S (…) Kaufmann E et 5 al. in Br J Surg

© The Author(s) 2026. Published by Oxford University Press on behalf of BJS Foundation Ltd.

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EUS-guided RFA shows promise for managing IPMNs

Endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) offers a safe, minimally invasive option for patients with branch-duct IPMNs who cannot undergo surgery.

  • Technical success reached 100% across 62 procedures, with local control in 98% of lesions.
  • Adverse events occurred in 27% of cases, mainly mild abdominal pain; no procedure-related deaths were reported.

This approach maintains pancreas-wide disease control in 80% of patients.

  • Smaller cysts and fewer worrisome features correlate with better outcomes.

Journal Article by Barras J, Lorenzo D (…) Barthet M et 2 al. in Gastrointest Endosc

Copyright © 2026 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.

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New model predicts treatment response in rectal cancer patients

A novel predictive model effectively identifies patients likely to achieve a pathological complete response after total neoadjuvant therapy for locally advanced rectal cancer, aiding in selection for watch-and-wait strategies.

  • In a study of 308 patients, the model predicted pCR with an area under the receiver operator curve (AUROC) of 0.71.
  • External validation in 83 patients showed the model predicted persistent clinical complete response (pCCR) with an AUROC of 0.69.

This tool enhances surgical decision-making, improving patient management in rectal cancer.

  • Model recalibration boosted predictive accuracy for pCCR to 0.17.

Journal Article by Varghese C, Ng JC (…) Larson DW et 5 al. in Ann Surg

Copyright © 2026 Wolters Kluwer Health, Inc. All rights reserved.

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Negligible benefit of terminal ileal intubation in asymptomatic colonoscopy

Routine terminal ileal intubation in asymptomatic patients undergoing colon cancer screening shows minimal diagnostic value.

  • Overall diagnostic yield for any ileal finding is just 1.74%.
  • Yield for clinically significant pathology is only 0.28%, with Crohn’s disease detection at 0.1%.

Surgeons should reconsider routine TII during screening and surveillance colonoscopies due to negligible benefit.

Review by Scalvini D, Maimaris S (…) Anderloni A et 14 al. in Gastrointest Endosc

Copyright © 2026 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.

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