Unplanned readmissions after esophagectomy are common and vary based on patient factors and surgical practices.

• Pooled readmission rate post-esophagectomy: 16.4%.
• Increased risk associated with comorbidities (diabetes, COPD, cardiovascular issues) and higher ASA status (III/IV).
• Longer hospital stays (>10 days) raise readmission odds by 35%.

Neoadjuvant therapy may reduce readmission risk.

• Complications, especially anastomotic leaks and thromboembolic events, contribute significantly to readmissions.

This study identifies the contact angle on preoperative CT images as a predictor for resection margins in ycT3 esophageal cancer patients, impacting surgical decision-making.

• Patients with positive resection margins had a contact angle of 130° vs. 93° for negative margins (p=0.0002).
• A contact angle ≥125° predicts positive margins with a sensitivity of 63% and specificity of 87% (AUC 0.76).
• Poorer prognosis is linked to CA ≥125°, with median survival of 11 months compared to 33 months for CA <125° (HR 1.83; p=0.03).

Consider using contact angle measurements to guide surgical strategies and patient counseling.

Achieving pathological complete response (pcr) after neoadjuvant chemotherapy significantly improves survival in gastric and esophagogastric junction cancers.

• Pcr correlates with a 63% lower risk of death (overall survival) using the Becker system.
• Progression-free survival is similarly improved, with a 38% reduction in risk of progression.

Consider prioritizing pcr as a key goal in treatment, especially with Becker criteria.

• The survival benefit is less pronounced in the major pathological response subgroup compared to pcr.