A meta-analysis of 15 studies with 982 patients demonstrated that gastric peroral endoscopic myotomy (G-POEM) is effective and safe for refractory gastroparesis regardless of etiology. Clinical success rates were 65% for diabetes, 70% for post-surgical, and 60% for idiopathic causes. G-POEM also improved Gastrointestinal Symptom Rating Scale Index (GCSI) scores significantly, with notable enhancements seen across all etiologies, suggesting its broad applicability and promising outcomes in treating this condition.
Review by Malik S, Loganathan P (…) Adler DG et 2 al. in Gastrointest Endosc
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