Ultra-early postoperative endoscopy within 24 hours significantly reduces anastomotic leaks after minimally invasive esophagectomy (MIE).

• Anastomotic leak rates dropped from 20.07% to 11.31% with ultra-early endoscopy (p=0.007).
• Hypoproteinemia rates fell from 21.90% to 9.49% (p<0.001), and median hospital stay decreased (p=0.01).

This approach safely enables earlier risk detection and promotes faster enteral nutrition, improving patient outcomes.

• No increase in adverse events or mortality was seen with ultra-early endoscopy.