Author: STITCHES Newsletter

Indocyanine green angiography reduces hypoparathyroidism risk after thyroid cancer surgery

Indocyanine green angiography identified 14.75% of devascularized parathyroids during thyroid cancer surgery. Patients with all four parathyroids evaluated by angiography had decreased rates of permanent hypoparathyroidism compared to those without. In fact, no patients in the indocyanine group developed permanent hypoparathyroidism. This method may help to prevent long-term hypoparathyroidism in individuals undergoing thyroid cancer surgery, […]

Computed Tomography-Based Vascular Burden Index Predicts Vascular Resection and Pathological Invasion in Pancreatic Cancer

Computed tomography-based vascular burden index accurately predicts vascular resection and pathological vascular invasion in pancreatic cancer patients post neo-adjuvant chemotherapy. The study found that the vascular burden index values, specifically around adjacent arteries and veins, significantly predicted vessel resection and invasion. These indices, particularly the regression of vvbi and avbi, were independent prognostic factors for […]

Augmented Reality System Enhances 3D Visualization in Liver Surgeries

An augmented reality (AR) system for laparoscopic liver surgery shows promise in improving visualization of internal anatomy. The system achieved a mean registration time of 2.4 minutes and a high accuracy rate of 93.8% in aligning preoperative 3D models with real-time laparoscopic images. Evaluations by surgeons demonstrate that this AR technology could significantly enhance tumor […]

Robot-assisted surgery excels in lymph node dissection for oesophageal cancer

Robot-assisted oesophagectomy shows superior effectiveness in removing crucial lymph nodes near the recurrent laryngeal nerve, compared to video-assisted techniques, resulting in lower rates of nerve injury. In a multicentre trial in Asia, robot-assisted surgery successfully dissected lymph nodes in 88.3% of cases, significantly outperforming video-assisted surgery at 69%. Robot-assisted procedures also led to fewer cases […]

Additional Gastrectomy after Endoscopic Submucosal Dissection Does Not Worsen Prognosis in Early Gastric Cancer

Propensity score-matching analysis of 778 patients showed that additional gastrectomy after endoscopic submucosal dissection (ESD) for early gastric cancer did not significantly impact overall or disease-free survival rates compared to surgery alone. Postoperative complication rates were similar between groups. The findings suggest that additional gastrectomy after ESD is oncologically acceptable and does not worsen long-term […]

Scissor-Type Knives Show Similar Efficacy in Colorectal Endoscopic Submucosal Dissection

Scissor-type knives, clutch cutter (CC) and SB knife Jr2 (SB), demonstrated comparable efficacy in colorectal endoscopic submucosal dissection. Both groups exhibited high en bloc resection rates and low complication rates, with CC showing significantly less perioperative bleeding than SB. Risk factors for prolonged procedure time included antiplatelet use, larger lesion size, severe fibrosis, and higher […]

Neoadjuvant Chemoradiotherapy Yields 84% 3-Year Survival for T4/N2 Rectal Cancer

Neoadjuvant chemoradiotherapy followed by total mesorectal excision resulted in a 3-year overall survival rate of 84% for patients with T4 and/or N2 rectal adenocarcinoma. Achieving R0 resection improved recurrence and survival rates, with T4 disease showing worse outcomes than N2. Adjuvant chemotherapy was associated with a survival benefit in the whole cohort and the N2 […]

Immune and Oxidative Stress-Related Genes as Targets for mRNA Vaccines in Pancreatic Cancer

Identification of potential mRNA vaccine targets in pancreatic cancer patients using immune- and oxidative stress-related genes. A model incorporating ERAP2, MET, CXCL9, and AGT genes predicts patient prognosis more accurately than current models. ERAP2 aids immune activation and cancer immune evasion, MET regulates cancer cell proliferation and invasion, CXCL9 expression is linked to poor prognosis […]