In a study covering 5165 cases across 149 hospitals, ranging from low to high volume, no significant differences emerged in post-operative outcomes, including morbidity, mortality, length of stay, readmissions, or total cost. These findings challenge the notion that hospital volume influences patient outcomes in HIPEC procedures for peritoneal carcinomatosis, suggesting comparable results across academic medical […]

In the clash of surgical approaches for advanced epithelial ovarian cancer, laparoscopic interval cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (L-CRS-HIPEC) outshone the open approach. With a significantly shorter hospital stay and faster return to systemic chemotherapy, L-CRS-HIPEC demonstrated comparable oncological outcomes. This study hints at the potential superiority of the laparoscopic approach in selected cases, […]

Embracing cytoreductive surgery (CRS) for peritoneal malignancies faces diverse challenges worldwide. This review explores the adoption of CRS, crucial in gastrointestinal and gynecological cancers, revealing significant global disparities. High-income countries lead in establishing CRS programs, while barriers in low- and middle-income nations persist. Access to advanced medical facilities, skilled teams, and funding shape this divide, […]

A study investigated the impact of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) on the quality of life (QoL) for patients taking opioids and psychotropic medications preoperatively. The research found that patients using these medications had worse baseline QoL but achieved similar scores to those who didn’t postoperatively, except in emotional functioning. The data suggests […]

A study examined cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) using paclitaxel and cisplatin in 22 patients with gastric cancer and peritoneal metastasis. Results showed that this treatment was well-tolerated with favorable oncologic outcomes. Patients experienced high rates of complete cytoreduction and R0 resection, and the treatment led to promising survival rates. Major complications […]

This study delves into the safety and effectiveness of combining hyperthermic intraoperative thoraco-abdominal chemotherapy (HITAC) with cytoreductive surgery (CRS) in patients with peritoneal carcinomatosis (PC) who need diaphragm resection. Researchers compared HITAC to traditional intraperitoneal chemotherapy (HIPEC). Results show that HITAC is a viable option with similar safety profiles, and it might offer benefits for […]

Researchers examined the role of mesenteric lymph nodes (MLNs) in digestive resection for advanced ovarian cancer (OC) with peritoneal metastases. Out of 159 patients, 77 underwent digestive resection, with 61.1% having MLNs examined, and 56.8% showed involvement. Surprisingly, MLN status didn’t significantly impact overall survival or progression-free survival. This calls for further systematic and standardized […]