Parathyroid glands in primary hyperparathyroidism exhibit distinct near-infrared autofluorescence (NIRAF) signatures, with normal glands showing higher intensity (2.68 vs 2.09 pixels, p

A systematic review assessed laparoscopic adrenalectomy (LA) for adrenal masses exceeding 5 cm, involving 963 patients across 25 studies. The mean tumor size was 7.05 cm, with the transperitoneal approach utilized for larger tumors averaging 12.10 cm. The average operative time was 137.4 minutes, with a minimal bleeding prevalence of 0.02%. Postoperative complications were rare, […]

Clinicians found that simple adrenal cysts smaller than 10 cm can be safely monitored without surgery. In a study of 77 patients, cysts under 10 cm grew slowly (0.3 cm/year) and showed no signs of malignancy or complications. Conversely, cysts over 10 cm grew significantly faster (13.2 cm/year) and were more likely to require surgical […]

Among 3,728 primary hyperparathyroidism patients, those undergoing parathyroidectomy had reduced risks of new-onset cognitive impairment (HR: 0.65), somnolence (HR: 0.45), and schizophrenia (HR: 0.08) compared to nonoperative management. No significant risk reduction was observed for anxiety, depression, or suicidal ideation. Additionally, surgical patients were less likely to require inpatient care for neuropsychiatric disorders (0.3% vs. […]

A >50% decrease in intraoperative parathyroid hormone (iPTH) levels into the normal reference range predicts complete excision of malignancy in patients with parathyroid carcinoma. 93% of patients achieving normal iPTH levels had operative success, compared to only 50% of those with a >50% iPTH decrease alone. This study suggests that iPTH monitoring, particularly when guiding […]

AI-based multimodal multi-tasks analysis of 1,011 PTC patients reveals molecular subtypes, impact of BRAF mutations on lymph node metastasis and prognosis. Deep learning model predicts metastasis with high accuracy (AUC 0.86-0.93) and generates heatmaps to aid clinicians in identifying high-risk areas. Offers valuable insights for precise risk stratification and personalized treatment decisions in PTC. • […]

Lobectomy is superior to total thyroidectomy in reducing complications, including transient parathyroid dysfunction, for intermediate-risk papillary thyroid carcinoma patients. Both lobectomy and total thyroidectomy show similar effects on survival outcomes and recurrence rates. This systematic review and meta-analysis suggest considering lobectomy as the optimal surgical approach for intermediate-risk papillary thyroid cancer, as total thyroidectomy does […]

Indocyanine green angiography identified 14.75% of devascularized parathyroids during thyroid cancer surgery. Patients with all four parathyroids evaluated by angiography had decreased rates of permanent hypoparathyroidism compared to those without. In fact, no patients in the indocyanine group developed permanent hypoparathyroidism. This method may help to prevent long-term hypoparathyroidism in individuals undergoing thyroid cancer surgery, […]

Anatomical variations of the recurrent laryngeal nerve (RLN) during thyroidectomy, such as extralaryngeal branching and relation to the inferior thyroid artery (ITA), significantly increase the risk of vocal cord paralysis (VCP). This retrospective study on 1070 neck sides found that extralaryngeal branching nerves had higher VCP rates compared to nonbranching nerves. RLN crossing anteriorly or […]

Radiofrequency ablation (RFA) demonstrates a 99.81% volume reduction rate with minimal complications in treating low-risk papillary thyroid microcarcinomas. Over 46.59 months follow-up, only 69 patients experienced local recurrence, positioning RFA as a compelling alternative to surgery and active surveillance. Notably, retreatment rates were significantly lower post-RFA, highlighting its effectiveness as a long-term treatment option with […]