Minimally invasive caudate lobectomy can lead to significant bleeding due to its proximity to the IVC, portal pedicle, and hepatic veins. Preoperative modeling and careful dissection techniques can help in safely managing the Spiegel/IVC interface during laparoscopic caudate resection, reducing the risk of thermal injury and ensuring successful outcomes. Journal Article by Salirrosas O, Harandi […]
Category: HPB & Spleen
Does palliative surgery improve outcomes in locally advanced pancreatic cancer?
Patients with locally advanced pancreatic cancer undergoing palliative surgery experienced slightly longer survival than those undergoing medical palliation, with hospital stays and readmission rates being significantly higher for the surgical group. Despite the marginal survival benefit, palliative surgery presents challenges in terms of hospitalization and risk of readmission. Journal Article by Kramer SP, Tonelli C […]
Elevated Postoperative AST/ALT Predicts Morbidity in Hepatocellular Carcinoma Resection
Elevated postoperative serum AST and ALT levels, measured as changes from preoperative values, were associated with increased postoperative morbidity in hepatocellular carcinoma patients undergoing curative resection. The optimal cutoff value for postoperative complications was identified as AST/ALT change ≥5. Routine use of AST and ALT can effectively predict the risk of complications after surgery for […]
Early-Onset Intrahepatic Cholangiocarcinoma: Poorer Survival and Altered Genomic Features
Patients with early-onset intrahepatic cholangiocarcinoma (ICC) had worse 5-year recurrence-free and disease-specific survival compared to patients with typical-onset ICC. Genomic analysis revealed distinct upregulated and downregulated genes in early-onset ICC. Morphologic and clinicopathologic characteristics could not fully explain the outcome differences between the two groups, highlighting the need for further research into early-onset ICC’s molecular […]
Significant Survival Benefit of Multimodality Treatment in Gallbladder Neuroendocrine Neoplasms
Gallbladder neuroendocrine neoplasms (GB NENs) are predominantly represented by neuroendocrine carcinomas. Outcomes analysis of 147 patients revealed a median overall survival (OS) of 6.14 months, with significant improvement to 20.20 months for those who received multimodality treatment versus 4.00 months for those who did not. These findings highlight the efficacy of multimodality approaches in improving […]
Endoscopic Treatment Outperforms Surgery in Necrotizing Pancreatitis
The study compared endoscopic and surgical treatment in acute necrotizing pancreatitis, showing that endoscopic treatment resulted in lower peri-interventional morbidity, shorter hospital stays, and lower mortality rates. Endoscopic treatment also led to better long-term outcomes with reduced renal insufficiency, ventilation dependency, and recurrence rates, along with improved exocrine functionality. These findings suggest a preference for […]
Comparison of laparoscopic liver resection outcomes in centers with and without liver transplant programs
Centers with liver transplant programs in France perform more difficult laparoscopic liver resections for hepatocellular carcinoma in cirrhotic patients compared to centers without transplant programs. Despite this complexity, both types of centers showed comparable safety and quality of care in terms of postoperative severe morbidity and mortality rates, demonstrating that all centers can achieve good […]
Repeat Resection for Recurrent Intrahepatic Cholangiocarcinoma Can Lead to Improved Survival
Repeat resection for recurrent intrahepatic cholangiocarcinoma in select patients can lead to improved survival compared to locoregional or palliative therapy alone. A 3-year post-recurrence survival rate of 47% was observed in surgically treated patients. Independent predictors of post-recurrence death included time to recurrence, site of recurrence, macrovascular invasion, and size of recurrence. Repeat resection was […]
Drain Clamping Technique: Effective Management of Persistent Biliary Fistulas After Liver Hydatid Cyst Surgeries
Researchers successfully treated persistent biliary fistulas post-liver hydatid cyst surgeries in 14 patients using a noninvasive drain clamping technique. All fistulas closed within 8-20 days without complications. This novel approach eliminated the need for surgical reoperation and resulted in complete recovery in patients, providing a safe and effective alternative to endoscopic procedures. Journal Article by […]
Portal Vein Stenting for Peri-hilar Cholangiocarcinoma: Clinical Benefits and Safety
Portal vein stenting in peri-hilar cholangiocarcinoma patients led to 100% technical success, improvement in 75% of clinical symptoms, and enabled anticancer therapy in 69% of cases. Complications occurred in 13%, including biliary injury and cholangitis, but patency was high at 86% after one year. Stent occlusion for tumor progression was managed successfully. This palliative treatment […]