In a study analyzing pancreatic cancer patients aged 80 years and above, it was found that non-home discharge after pancreatoduodenectomy (PD) was more than twice as likely to occur in this age group compared to those aged 65-79 years. Comorbidity factors such as COPD, hypertension, heart failure, and lower preoperative albumin were significantly associated with […]
Category: HPB & Spleen
The impact of diabetes mellitus on outcomes in patients undergoing surgical pancreatectomy for pancreatic diseases
A retrospective analysis of 370 patients who underwent pancreatic resection surgery in Austria revealed that the incidence of postoperative diabetes mellitus (postopdm) was 29%. Postopdm occurred significantly more frequently in patients with malignant pancreatic diseases compared to benign diseases (31.3% vs. 16.7%). The study highlights the prominence of diabetes mellitus as a risk factor for […]
Portal Hypertension Assessment Crucial for Hepatocellular Carcinoma Resection Decision
Indirect signs of portal hypertension (pht) don’t raise complications risk in hepatocellular carcinoma (HCC) patients undergoing liver resection (LR). However, in patients with hepatic venous pressure gradient (HVPG) ≥10 mmHg, LR significantly increases overall morbidity and liver-related complications risk. Transjugular HVPG assessment is crucial for LR decisions, with a minimally invasive approach showing favorable outcomes, […]
Distal Fistula Risk Score: Preoperative Tool for Predicting Pancreatic Fistula in Distal Pancreatectomy
Researchers conducted a nationwide retrospective Dutch cohort study to validate the preoperative and intraoperative Distal Fistula Risk Score (D-FRS) for postoperative pancreatic fistula (POPF) prediction in distal pancreatectomy (DP) patients. The study included 896 patients, of which 152 (17%) developed POPF. The preoperative D-FRS, based on pancreatic neck thickness and pancreatic duct diameter, had an […]
Low Utilization of Surgical Resection for Locally Advanced Pancreatic Cancer
Despite the positive outcomes reported by high-volume international centers, a multicenter retrospective study in the Netherlands found that surgical resection for locally advanced pancreatic cancer (LAPC) following induction chemotherapy is infrequently performed. Out of 142 patients who underwent resection, only 34.5% met the national comprehensive cancer network criteria. The most commonly used chemotherapy was FOLFIRINOX, […]
Robotic Ramps Safely Improves Short-Term Outcomes for Pancreatic Cancer Patients
A retrospective cohort study compared robotic and open radical antegrade modular pancreatosplenectomy (ramps) for pancreatic ductal adenocarcinoma (PDAC) and found that robotic ramps had advantages in operative time, estimated blood loss, delayed gastric emptying, and postoperative hospital stay. The rate of severe postoperative complications was similar between the groups. Both robotic and open ramps had […]
EUS-Fiducial Markers Improve Pancreas Surgery Guidance
Researchers conducted a preliminary controlled trial to evaluate the feasibility of using endoscopic ultrasound-guided fiducial markers (EUS-FMP) to guide pancreas surgery. The study enrolled 20 patients with resectable pancreas masses and found that EUS-FMP was successful and technically straightforward before planned surgery. Intraoperative detection of the markers was feasible and improved compared to lesions without […]
Estimating the Rate of Low-Yield Surgery in Pancreatic Cancer Surveillance
The prevalence meta-analysis aimed to determine the rate of low-yield surgery in pancreatic cancer surveillance. A systematic search of relevant studies was conducted, including 5027 patients from 23 articles. The pooled prevalence of low-yield surgery was found to be 2.1%, with a slightly higher prevalence among familial pancreatic cancer subjects without known pathogenic variants. The […]
Low Accuracy of Preoperative Imaging in Detecting Lymph Node Metastasis in Pancreatic Neuroendocrine Tumors
A multi-institutional study investigated the accuracy of preoperative imaging in detecting lymph node metastasis (lnm) in patients with pancreatic neuroendocrine tumors (pnets). They found that traditional imaging modalities such as computed tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET)-CT, and octreoscan had low sensitivities to determine nodal status. Preoperative imaging indicating nodal involvement […]
Minimally invasive repeat hepatectomy is a safe alternative to open repeat hepatectomy
A cohort study comparing minimally invasive repeat hepatectomy (MIRH) and open repeat hepatectomy (ORH) revealed that MIRH is a feasible and safe approach after previous open hepatectomy. Among 46 patients included in the study, 43% underwent MIRH and 57% underwent ORH. MIRH was associated with less blood loss and shorter length of stay compared to […]