In metastatic Grade 1 gastro-entero-pancreatic neuroendocrine tumors (GEP-NETs), a higher burden of liver disease significantly reduces progression-free survival (PFS). Patients with concomitant extra-hepatic involvement have a lower overall survival (OS) rate. Liver tumor burden emerged as the sole predictor of PFS. These findings suggest a need for more aggressive treatment strategies in metastatic Grade 1 […]
Category: HPB & Spleen
Quality Metric Adherence and Survival in Pancreatic Cancer Patients
Adherence to surgical quality metrics in pancreatic ductal adenocarcinoma resections significantly correlates with improved overall survival. A study of 38,228 patients revealed that higher quality metric scores led to better outcomes, with mortality hazards decreasing in a stepwise manner. These findings emphasize the importance of quality metric compliance in enhancing long-term survival for patients undergoing […]
Robotic Assisted Common Bile Duct Exploration in Complex Gallstone Disease
Robotic-assisted cholecystectomy with common bile duct exploration provides a single-stage solution for complex gallstone disease. A series of emergent and expedited robotic procedures showed feasibility, safety, and effectiveness in treating patients. The robotic platform, alongside innovative adjuncts, enhances precision and outcomes in managing complex gallstone disease. Results indicate successful clearance of bile duct stones, low […]
Risk Stratification in HCC Patients with VWF-Ag Levels
Von Willebrand Factor Antigen serves as a non-invasive biomarker for clinically significant portal hypertension and predicts time to recurrence and overall survival in hepatocellular carcinoma patients undergoing liver resection. VWF-Ag levels higher than 291% identify a high-risk group with increased posthepatectomy liver failure incidence, while levels of 182% or lower indicate suitability for surgery. VWF-Ag […]
Superior Predictive Models for Posthepatectomy Liver Failure
Novel machine learning models demonstrated better performance in predicting clinically significant posthepatectomy liver failure compared to traditional clinical scores, with pre- and postoperative artificial neural network models achieving excellent accuracy. These online interpretable models could serve as valuable decision support tools for identifying high-risk patients before and after surgery, potentially improving outcomes and mortality rates. […]
Tumor Burden Score as a Prognostic Factor
Researchers found that Tumor Burden Score (TBS) significantly influences survival in hepatocellular carcinoma (HCC) patients post-resection. A retrospective analysis of 291 patients showed median overall survival (OS) of 107.4 months for BCLC stage A and 42.7 months for stage B with low TBS. High TBS patients had median OS of 42.3, 25.72, and 16.9 months […]
Improved Surgical Planning with Liver MRI in Patients with Colorectal Liver Metastases
Liver MRI led to a 24.12% change in local treatment plans for patients eligible for surgical resection or ablation of colorectal liver metastases, based on CT findings. This study highlights the significant added value of liver MRI, particularly with contrast-enhanced imaging and diffusion-weighted sequences, in guiding preinterventional decision-making. Further large prospective studies are warranted to […]
Improved Visualization and Diagnostic Accuracy in Biliary Strictures with Virtual Indigo Carmine Chromoendoscopy
Virtual Indigo Carmine Chromoendoscopy (VICI) converted from peroral cholangioscopy images using artificial intelligence technology demonstrated superior visualization of surface structures and lesion margins compared to white light imaging and narrow-band imaging. VICI, in combination with white light imaging, significantly improved diagnostic accuracy for biliary strictures, showing potential as a supportive modality for peroral cholangioscopy. Journal […]
Long-Duration Neoadjuvant FOLFIRINOX Therapy for Pancreatic Cancer Surgery
Study shows similar survival outcomes in pancreatic cancer patients who undergo surgery after long-duration neoadjuvant FOLFIRINOX therapy, regardless of pretreatment resectability status. The majority received FOLFIRINOX alone without radiation, achieving a 76% R0 resection rate. Median overall survival was 41 months and did not vary by disease stage. This research underscores the potential for favorable […]
Day-case robotic liver resection: safety and feasibility
Day-case robotic liver resection is safe and feasible, with 65% of patients discharged within 24 hours. No major complications or mortalities were reported in this case series, indicating the potential for a shorter hospital stay and improved recovery. Implementation of follow-up pathways is crucial for monitoring and timely intervention. This study showcases the safety and […]