Category: HPB & Spleen

High Mortality and Morbidity Rates in Patients at High Risk for Postoperative Pancreatic Fistula

Researchers analyzed nationwide outcomes after pancreatoduodenectomy in patients at very high risk for postoperative pancreatic fistula (POPF). The study found a 4.1% in-hospital mortality rate and observed major morbidity in 45.9% of patients. POPF occurred in 30% of patients, leading to increased major morbidity and mortality rates. Prophylactic total pancreatectomy (TP) was performed in only […]

Development of Prediction Models for Major Morbidity and Endocrine Dysfunction after Central Pancreatectomy

A retrospective multicenter study aimed to develop prediction models for major morbidity and endocrine dysfunction following central pancreatectomy (CP). The study included 838 patients from 51 centers in 19 countries. The risk model for major morbidity identified male sex, age, BMI, and ASA score ≥3 as significant factors. The risk model for endocrine dysfunction revealed […]

An Operative Time Threshold for Safety in Robotic Pancreaticoduodenectomy

Robotic pancreaticoduodenectomy (RPD) is a safe and effective procedure, although it often takes longer than open pancreaticoduodenectomy (OPD). A study analyzed elective, low-risk RPD and OPD cases to determine the operative time threshold (OTT) for safety in RPD patients. The OTT was identified as 7.7 hours, and patients whose RPD exceeded this threshold had higher […]

Understanding the Levels of Robotic Mesopancreas Dissection According to Malignancy and Vascular Anatomy

A recent study provides a comprehensive step-by-step overview of mesopancreas dissection during robotic pancreatoduodenectomy (PD) and its three levels based on tumor type. Surgeons interested in the robotic approach for PD should be familiar with these levels to ensure safe and successful dissections. The study aims to familiarize clinicians with tips and indications related to […]

Splenic Vein Tumor Thrombosis is an Independent Prognostic Factor in Distal Pancreatic Adenocarcinoma

The study aimed to assess the prognostic relevance of splenic vessel involvement in distal pancreatic adenocarcinoma. The researchers identified 149 patients who underwent surgery, with 46.3% showing splenic vascular involvement. Among them, 14.8% had a pathologic tumor thrombosis of the splenic vein. The presence of splenic vein tumor thrombosis was associated with larger tumors, more […]

High Rate of Misdiagnosis of Suspected Cancer Found in Pancreatoduodenectomy Patients Over Three Decades

Researchers investigated the misdiagnosis of suspected cancer among patients undergoing pancreatoduodenectomy (PD) over a 30-year period. They found that diagnostic errors resulted in PD being mistakenly performed for benign disease. Of the 1,812 patients who underwent PD for suspected malignancy, 97 (5.2%) were ultimately diagnosed with a benign condition. The study also highlighted the challenges […]

Lymph Node Dissection on Intrahepatic Cholangiocarcinoma: Potential Benefit only for Clinically Node-Negative Patients

According to a systematic review and meta-analysis, researchers found that lymph node dissection (LND) did not significantly impact overall survival, disease-free survival, or risk of major complications in patients with intrahepatic cholangiocarcinoma (ICC). However, for clinically node-negative patients, LND was associated with improved overall survival and a trend towards improved disease-free survival compared to no […]

Perioperative Oral Care Management Reduces Surgical Site Infections after Pancreaticoduodenectomy

A retrospective multicenter analysis involving 503 patients who underwent pancreaticoduodenectomy revealed that perioperative oral care management significantly reduces the incidence of organ/space surgical site infections. Patients who received oral care management had a lower rate of complications compared to those who did not. The study also identified hypertension and lack of perioperative oral management as […]

58.2% of Distal Pancreatectomies Achieve Textbook Outcomes

The study aimed to determine the textbook outcome in distal pancreatectomy by analyzing a multicenter database. The specific definition of textbook outcome included factors such as hospital stay, complications, mortality, readmission, and absence of pancreatic fistula. Among the 450 patients included, 58.2% achieved textbook outcomes. Prolonged hospital stay was the most common factor associated with […]

Prognosis of Laparoscopic Hepatectomy for BCLC Stage 0/A HCC with Clinically Significant Portal Hypertension

Patients with BCLC stage 0/A hepatocellular carcinoma (HCC) and clinically significant portal hypertension (CSPH) who underwent laparoscopic hepatectomy had worse overall and recurrence-free survival rates compared to those without CSPH. However, CSPH patients treated laparoscopically had better short- and long-term prognoses than those treated with open surgery. This study highlights the importance of careful patient […]