Category: HPB & Spleen

Effective Treatment for End-Stage Hepatic Hydatid Disease

Two-step vascular exclusion and in situ hypothermic portal perfusion during liver resection proves safe and effective for patients with advanced hepatic hydatidosis. With minimal complications and reduced anhepatic time, this technique allows for successful surgical treatment, resulting in good postoperative recovery and shortened hospital stays. Overall, this approach demonstrates promising outcomes in managing end-stage hepatic […]

Positive outcomes of robotic surgery in hepatobiliary oncology

Robotic surgery in hepatobiliary oncology, using the da Vinci Xi system, resulted in favorable patient outcomes with a low conversion rate, no postoperative mortality, and high 5-year overall survival and disease-free survival rates. Patient selection was crucial for success. The study highlights the technical superiority and safety of robotic hepatobiliary surgery, demonstrating feasibility and efficacy […]

Dilatation of Pancreatic Duct Post-PD Linked to Exocrine Function Impairment

Researchers found that 21.7% of patients developed main pancreatic duct (MPD) dilatation 1 year after pancreatoduodenectomy (PD), which was significantly associated with impaired exocrine function. Endocrine function, nutritional status, and fatty liver development were not affected. A serum total protein level ≥7.3 g/dL was identified as an independent predictor for MPD dilatation. The mean MPD […]

High Serum Amylase Predicts Pancreatic Fistula After Surgery

Serum amylase ≥120 IU/L on postoperative day one is a robust predictor of postoperative pancreatic fistula after pancreaticoduodenectomy. In a study of 132 patients, high serum amylase level, soft pancreatic texture, and high-risk pathology were independent risk factors for fistula development. For patients with soft texture, serum amylase ≥120 IU/L showed a significantly higher risk. […]

Reducing Postoperative Pancreatic Fistulas with Coverage Techniques

Postoperative pancreatic fistulas are a significant issue following partial pancreatectomy. A meta-analysis of 18 randomized clinical trials involving 2326 patients revealed that both artificial and autologous coverage techniques reduced the incidence of postoperative pancreatic fistulas by 29%. Specifically, autologous coverage was even more effective for patients undergoing distal pancreatectomy. This study highlights the positive impact […]

High Response Rate and Survival in Unresectable Hepatocarcinoma Treatment

Targeted therapy plus immunotherapy combined with hepatic arterial infusion chemotherapy (FOLFOX) showed a 60.4% objective response rate and 83.0% one-year overall survival in patients with unresectable hepatocellular carcinoma. The regimen demonstrated a 34.0% surgical conversion rate, with manageable adverse events. These findings suggest a promising curative approach for unresectable HCC patients, highlighting the efficacy and […]

Enhanced Precision in Laparoscopic Left Hemihepatectomy for Hepatolithiasis

Augmented reality navigation combined with indocyanine green fluorescence imaging significantly improves safety and precision in laparoscopic left hemihepatectomy for hepatolithiasis. The new method successfully aided in guiding hilar vessel dissection and identifying liver resection boundaries, with no major complications reported. This combined approach offers enhanced surgical accuracy and may be particularly beneficial when fluorescence imaging […]

Machine Learning Predictive Model for Distal Cholangiocarcinoma Recurrence

Integration of machine learning into prognostic modeling for distal cholangiocarcinoma yielded a robust predictive model for disease-free survival after pancreaticoduodenectomy. Significant predictors of recurrence included lnr15, neural invasion, n stage, surgical radicality, and differentiation grade. The model demonstrated strong discriminatory capacity with internal and external validations showing high accuracy levels. This tool can enhance tailored […]

Radiological Marker Correlates with Tumor Budding in Pancreatic Cancer

Pancreatic cancer’s radiomorphological appearance on MRI correlates with tumor budding, a marker of poor prognosis. Intermediate to high spiculation on MRI was seen in 64% of tumors, with over 90% showing tumor buds. A positive correlation existed between MRI spiculation grade and histopathological tumor bud density. This radiological marker may help identify patients needing extensive […]

Artificial intelligence predicts non-transplantable recurrence in hepatocellular carcinoma

Artificial intelligence models accurately predicted non-transplantable recurrence in hepatocellular carcinoma patients post-hepatic resection. An ensemble AI model showed high accuracy (AUC 0.751-0.858) with incorporation of postoperative factors. Radiologic tumor burden and microvascular invasion were key predictors. Patients with predicted recurrence had lower survival rates, highlighting the models’ prognostic value. The AI models could guide treatment […]