Category: HPB & Spleen

Prognostic Model for Unresectable Gastric Cancer Liver Metastases

Study establishes a reliable nomogram model with five independent risk factors for gastric cancer liver metastases. The model accurately predicts patient prognosis, showing promising predictive accuracy and clinical benefit for outcome evaluation. Results demonstrate high area under the curve values at 1, 3, and 5 years, excellent consistency in calibration curves, and substantial net clinical […]

Management and Prognosis of Ruptured Hepatocellular Carcinoma

Spontaneous rupture of hepatocellular carcinoma (RHCC) presents a life-threatening complication in 3-15% of patients with HCC. Recent studies show improved survival benefits with transcatheter arterial embolization followed by elective hepatectomy. Despite poor prognosis, active surveillance and multidisciplinary management strategies can enhance short- and long-term outcomes. Achieving hemostasis and stabilizing patients remain crucial in RHCC management, […]

Improved Survival Prediction in Intrahepatic Cholangiocarcinoma

Preoperative CT radiomics of intrahepatic cholangiocarcinoma and peritumoral tissue enhances survival prediction. Combined with clinical data, the radiomic model achieves equivalent prognostic estimates compared to postoperative pathology. In a study of 215 patients, the addition of radiomic features led to a significant improvement in overall and progression-free survival predictions. Consideration of both portal and arterial […]

Combination Therapy Improves Survival in Early-Onset Pancreatic Cancer

Study on non-metastatic early-onset pancreatic cancer patients showed postoperative survival improvement with adjuvant therapy. Surgery followed by neoadjuvant and adjuvant therapy recommended for locally advanced cases. 1-year, 2-year, and 3-year overall survival rates were 84.3%, 51.5%, and 27.6% respectively. Findings suggest a positive impact of combination therapy including surgery, radiotherapy, and chemotherapy on survival outcomes […]

Adjuvant Chemotherapy Benefits Post-Pancreaticoduodenectomy

Adjuvant therapy following pancreaticoduodenectomy for pancreatic adenocarcinoma shows improved overall survival. Patients who responded favorably to neoadjuvant therapy may not benefit from additional adjuvant treatment. Downstaging after neoadjuvant therapy is a key factor in determining the efficacy of adjuvant therapy post-surgery. The study highlights the importance of personalized treatment strategies based on individual patient responses […]

Improved Recurrence Prevention with Anatomical Liver Resection for Hepatocellular Carcinoma

Anatomical liver resection (AR) significantly reduces local and early recurrence rates compared to nonanatomical liver resection (NR) in patients with solitary hepatocellular carcinoma (HCC) ≤5cm. AR group exhibited lower recurrence rates, improved overall survival, and fewer instances of early recurrence. NR was identified as an independent risk factor for early recurrence and a prognostic factor […]

Middle Colic Artery: A Key Landmark in Laparoscopic Pancreatoduodenectomy

Exposing the middle colic artery (MCA) first in laparoscopic pancreatoduodenectomy allows for safe and efficient determination of the superior mesenteric artery (SMA), first jejunal artery (J1A), and inferior pancreatoduodenal artery (IPDA). An anatomical correlation study found that 90.9% of MCA started at 12-3 o’clock from SMA, with mean distances of 56.4 mm to MCA, 37.4 mm to […]

Chemoradiotherapy Post-Neoadjuvant Chemotherapy Boosts Survival in High-Risk Pancreatic Cancer

Adjuvant chemoradiotherapy post-multiagent neoadjuvant chemotherapy in pancreatic cancer patients enhances survival, especially for those with lvi+ or grade iii tumors. While initial unadjusted analysis showed shorter median survival with chemoradiotherapy, adjusted results indicated a 25% risk reduction in mortality. Notably, patients with grade iii or lvi+ tumors reaped the most benefit from this combined adjuvant […]

Cost-effectiveness of Liver Resection Techniques

Laparoscopic liver resection proves most cost-effective with lower total costs and superior postoperative outcomes compared to open and robotic liver resection. Open liver resection incurs the lowest procedural costs, but highest hospitalization costs. Robotic liver resection has the highest total and procedural costs but reduces hospitalization costs with advantages in mortality and length of stay. […]

Left-Sided Colon Cancer Shows Better Survival Than Rectal Cancer Post-Hepatic Metastasectomy

Survival outcomes differed between left-sided colon and middle/low rectal cancer post-colorectal hepatic metastasectomy. Patients with left-sided colon cancer exhibited significantly better overall survival (OS) than those with middle/low rectal cancer, especially in the subgroup analysis of ras mutations. The study suggests that middle/low rectal cancer should not be grouped together with left-sided colon cancer in […]