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J Gastrointest Surg29 Jun 2024

Postoperative Pancreatic Fistula Increases Complications in Pancreatoduodenectomy

Analysis of American College of Surgeons data revealed a 1.98% 30-day mortality rate in patients undergoing pancreatoduodenectomy according to International Study Group of Pancreatic Surgery criteria. Postoperative pancreatic fistula (POPF) correlated with higher complications, readmission, and mortality rates, with males at higher risk than females…

J Gastrointest Cancer29 Jun 2024

Liver Tumor Burden Predicts Prognosis in Metastatic Grade 1 GEP-NETs

In metastatic Grade 1 gastro-entero-pancreatic neuroendocrine tumors (GEP-NETs), a higher burden of liver disease significantly reduces progression-free survival (PFS). Patients with concomitant extra-hepatic involvement have a lower overall survival (OS) rate. Liver tumor burden emerged as the sole predictor of PFS. These findings suggest a…

BMC Surg28 Jun 2024

Quality Metric Adherence and Survival in Pancreatic Cancer Patients

Adherence to surgical quality metrics in pancreatic ductal adenocarcinoma resections significantly correlates with improved overall survival. A study of 38,228 patients revealed that higher quality metric scores led to better outcomes, with mortality hazards decreasing in a stepwise manner. These findings emphasize the importance of…

Int J Surg28 Jun 2024

Robotic Assisted Common Bile Duct Exploration in Complex Gallstone Disease

Robotic-assisted cholecystectomy with common bile duct exploration provides a single-stage solution for complex gallstone disease. A series of emergent and expedited robotic procedures showed feasibility, safety, and effectiveness in treating patients. The robotic platform, alongside innovative adjuncts, enhances precision and outcomes in managing complex gallstone…

Ann Surg Oncol27 Jun 2024

Risk Stratification in HCC Patients with VWF-Ag Levels

Von Willebrand Factor Antigen serves as a non-invasive biomarker for clinically significant portal hypertension and predicts time to recurrence and overall survival in hepatocellular carcinoma patients undergoing liver resection. VWF-Ag levels higher than 291% identify a high-risk group with increased posthepatectomy liver failure incidence, while…

Int J Surg27 Jun 2024

Superior Predictive Models for Posthepatectomy Liver Failure

Novel machine learning models demonstrated better performance in predicting clinically significant posthepatectomy liver failure compared to traditional clinical scores, with pre- and postoperative artificial neural network models achieving excellent accuracy. These online interpretable models could serve as valuable decision support tools for identifying high-risk patients…

HPB (Oxford)26 Jun 2024

Tumor Burden Score as a Prognostic Factor

Researchers found that Tumor Burden Score (TBS) significantly influences survival in hepatocellular carcinoma (HCC) patients post-resection. A retrospective analysis of 291 patients showed median overall survival (OS) of 107.4 months for BCLC stage A and 42.7 months for stage B with low TBS. High TBS…

Gastrointest Endosc25 Jun 2024

Improved Visualization and Diagnostic Accuracy in Biliary Strictures with Virtual Indigo Carmine Chromoendoscopy

Virtual Indigo Carmine Chromoendoscopy (VICI) converted from peroral cholangioscopy images using artificial intelligence technology demonstrated superior visualization of surface structures and lesion margins compared to white light imaging and narrow-band imaging. VICI, in combination with white light imaging, significantly improved diagnostic accuracy for biliary strictures,…

Ann Surg Oncol25 Jun 2024

Long-Duration Neoadjuvant FOLFIRINOX Therapy for Pancreatic Cancer Surgery

Study shows similar survival outcomes in pancreatic cancer patients who undergo surgery after long-duration neoadjuvant FOLFIRINOX therapy, regardless of pretreatment resectability status. The majority received FOLFIRINOX alone without radiation, achieving a 76% R0 resection rate. Median overall survival was 41 months and did not vary…