Researchers reviewed advances in diagnosis and management of hepatic adenomas (HA), classified into at least eight subtypes. MRI is the best imaging method for diagnosis and can differentiate among subtypes. HA larger than 5cm have higher risks of bleeding and malignancy and should be resected. A high risk of malignant transformation was found in β-catenin […]
Category: HPB & Spleen
Enhanced Overall Survival and Tumor Reduction in EUS-RFA for Unresectable Pancreatic Adenocarcinoma
Researchers assessed EUS-RFA in 26 patients with unresectable pancreatic ductal adenocarcinoma, showing technical success in all cases and no major adverse events. Six months post-EUS-RFA, 42.3% of patients had improved overall survival and significant performance status enhancement. Tumor reduction and post-treatment necrotic areas were observed, while metastatic disease negatively impacted survival. EUS-RFA proved safe and […]
Successful laparoscopic and robotic s7 segmentectomy using ICG-enhanced compression for hepatocellular carcinoma
ICG-enhanced compression anatomical segment 7 segmentectomy in laparoscopic and robotic approach was successfully performed in two cases of Child-Pugh class A hepatocellular carcinoma. The technique enabled identification and resection of posterosuperior lesions with minimal liver stiffness and no postoperative complications, achieving R0-resection margins and quick patient discharge, showcasing feasibility and reliability for future adoption. Journal […]
Development of a 10-Point Score to Predict Post-Recurrence Survival in Intrahepatic Cholangiocarcinoma
Researchers developed a 10-point score to predict post-recurrence survival (PRS) in patients with intrahepatic cholangiocarcinoma (iCC) following resection. This score successfully stratified patients based on their PRS likelihood, with lower scores associated with higher survival rates. The score included factors like tumor grade, resection margin, and specific tumor markers, providing valuable guidance for treatment decisions […]
Preoperative chemotherapy improves overall survival in liver-limited metastasis from gastric cancer
Preoperative chemotherapy significantly increased overall survival in patients with liver-limited metastasis from gastric cancer who underwent hepatectomy, compared to upfront surgery. Patients who exhibited a partial response to preoperative chemotherapy had better outcomes than those with stable or progressive disease. The preoperative chemotherapy group also had a higher chance of undergoing surgical resection for recurrent […]
Comparison of Long-Term Outcomes between Spleen-Preserving Distal Pancreatectomy with Splenic Vessel Resection and Preservation
Long-term outcomes of spleen-preserving distal pancreatectomy with splenic vessel resection showed higher prevalence of perigastric varices and lower platelet count compared to preservation. However, other complications such as gastric submucosal varices, splenic infarction, gastrointestinal bleeding, and hematologic parameters were similar between the two groups 5 years post-surgery. Spleen preserving distal pancreatectomy with splenic vessel preservation […]
Adenocarcinoma Arising from Intraductal Papillary Mucinous Neoplasms (A-IPMN) Shows Superior Long-term Outcomes Compared to Pancreatic Ductal Adenocarcinoma (PDAC)
Patients with Adenocarcinoma arising from Intraductal Papillary Mucinous Neoplasm (A-IPMN) have better long-term survival and lower recurrence rates compared to those with Pancreatic Ductal Adenocarcinoma (PDAC). PDAC patients showed inferior overall and disease-free survival, higher locoregional recurrence rates, but comparable systemic recurrence rates. A-IPMN patients had higher rates of lung and peritoneal recurrence but lower […]
Which type of pancreatic surgery has the best postoperative quality of life?
After reviewing 45 articles on quality of life post-pancreatic surgery, it was found that recovery time varied between surgeries. Duodenum-preserving pancreatic head resection showed better quality of life compared to pancreaticoduodenectomy, with central pancreatectomy outcomes still debated. Recovery to preoperative levels took longer after total pancreatectomy. The decrease in exocrine and endocrine functions significantly impacted […]
Optimizing Neoadjuvant Chemotherapy for Initially Resectable Colorectal Cancer Liver Metastasis
Neoadjuvant chemotherapy for initially resectable colorectal cancer liver metastasis aims at tumor downsizing, evaluating biological behavior, and reducing postoperative recurrence risk. Balancing tumor reduction benefits with hepatic injury risks and the need for timely surgery is crucial. Precision medicine’s role in tailoring neoadjuvant regimens, such as gene testing, and a multidisciplinary approach are emphasized. Tailored […]
Long-term indwelling stents reduce recurrence in pancreatic fluid collections post-drainage
When comparing long-term indwelling plastic stents (LTIS) to standard stent removal (SSR) after resolving pancreatic fluid collections (PFC) with endoscopic transmural drainage (ETD), LTIS showed significantly lower recurrence rates (3% vs. 23%). LTIS also decreased the need for further interventions. This meta-analysis of 16 studies and 1285 patients indicates that LTIS is safer and more […]