Researchers found that agile 3+ and agile 4 scores from vibration-controlled transient elastography had the highest discriminatory power in predicting liver-related events in patients with metabolic dysfunction-associated steatotic liver disease. These scores accurately categorized patients between high and low risk categories, with a decrease in agile 3+ score by more than 20% linked to a […]

Utilizing the SMA-first approach in robotic pancreaticoduodenectomy (RPD) resulted in notable improvements in surgery for pancreatic cancer. The technique involved early dissection of the superior mesenteric artery (SMA) from the posterior aspect, facilitating a more systematic mesopancreatic dissection. The approach, demonstrated in a video, included a standardized SMA-first technique and triangle clearance, showing promising results […]

Metabolic dysfunction-associated steatotic liver disease (MASLD) has become a leading cause of liver transplantations in western countries, with metabolic dysfunction-associated steatohepatitis (MASH) progressing to fibrosis, cirrhosis, and liver failure. Researchers anticipate the approval of the first drug for MASH by 2024, exploring pathways like thyroid hormone receptors and peroxisome proliferator-activated receptors. Phase 3 trials focus […]

Long-term surveillance of IPMNs led to early diagnosis and better outcomes of concomitant PDAC. Patients with IPMNs had higher rates of early cancer stage identification and R0 resection compared to those without IPMNs. Concomitant PDACs were associated with longer overall survival, with a 5-year survival rate higher than non-IPMN-associated PDACs. This study highlights the importance […]

Researchers analyzed 727 pancreatic cancer patients who received neoadjuvant therapy and pancreatectomy from 1998 to 2018. They found an increase in neoadjuvant chemotherapy use and a shift in the timing of recurrence risk from postoperative year 1 to year 2. Overall survival improved over time, predominantly due to better post-recurrence survival rates. Recurrence rates remained […]

Researchers explore the concept of biologic resectability in defining patient selection for metastasectomy in oligometastatic pancreatic ductal adenocarcinoma (PDAC). They assess safety and oncologic outcomes of metastasectomy in liver, peritoneum, and lung, and evaluate biomarkers like radiographic findings, biochemical markers (CA 19-9, CEA), and inflammatory markers. The study emphasizes the importance of considering biologic, rather […]

Combining the Glissonean approach and indocyanine green fluorescence imaging aids in performing laparoscopic right anterior sectionectomy with precision, particularly in locating transection planes near the middle and right hepatic veins. In a case study, this technique enabled successful resection of a hepatocellular carcinoma with minimal blood loss and a short postoperative recovery period. Improved guidance […]

Robotic and laparoscopic approaches to minimally invasive pancreatoduodenectomy yield similar oncologic and surgical outcomes in pancreatic cancer patients, with a lower conversion rate to open surgery for the robotic cohort. The learning curve has a significant impact on outcomes, with higher-volume centers showing improved results, particularly in reducing 90-day mortality. Journal Article by Wehrle CJ, […]

Analysis of 817 patients after pancreaticoduodenectomy revealed that 19.5% developed postoperative pancreatic fistula (popf), with 45.9% being post-pancreatectomy acute pancreatitis (ppap)-associated popf. These patients had higher morbidity and distinct risk factors (blood loss, pancreatic texture) compared to non-ppap-associated popf. Non-ppap-associated popf was linked to age, gender, and pancreatic duct size. Regardless of risk scores, the […]