In patients with colorectal peritoneal metastases (CRC-PM) treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC), systemic chemotherapy (SC) did not significantly enhance overall survival (OS). However, the timing of SC made a difference. Preoperative SC correlated with more major complications and shorter disease-free intervals, while postoperative SC resulted in longer disease-free intervals. The study […]
Category: Intestine and Lower Gastrointestinal Tract
MRI Scoring Sheds Light on Post-Op Anorectal Function in Rectal Cancer
In a two-center study, researchers established a postoperative MRI-based scoring system for fibrosis in locally advanced rectal cancer patients who received neoadjuvant chemoradiotherapy (NCRT). They found a positive correlation between anastomotic and perirectal fibrosis scores (AFS and PFS) and anorectal function, measured using the Wexner score. Age, tumor height, AFS, and PFS were identified as […]
Comparing Strategies for Anastomotic Leak After Rectal Cancer Surgery
A worldwide study investigated the treatment of anastomotic leaks following rectal cancer surgery, categorizing strategies into salvage surgery, passive or active drainage, and no initial faecal diversion. Among 2470 patients, the study found that primary salvage surgery and omitting faecal diversion represented the most severe and least severe cases, respectively. In patients with diverted leaks, […]
Clinical Calculator Accurately Predicts Freedom from Colon Cancer Recurrence
In a study validating the Memorial Sloan Kettering clinical calculator for predicting freedom from colon cancer recurrence, results demonstrated its accuracy. The calculator, based on clinical and molecular variables, was originally developed with selective microsatellite instability testing. However, when tested with data from patients thoroughly examined for instability, it remained reliable. The concordance index was […]
Preoperative Chemo Ups Survival in Nonmetastatic T4b Colon Cancer
A game-changer for colon cancer treatment! This study analyzed the impact of preoperative chemotherapy on nonmetastatic T4b colon cancer. Results showed that neoadjuvant chemotherapy significantly increased survival rates. Over the years, its use grew from 4% to 16%. Factors like younger age, male gender, recent diagnosis, academic centers, node-positive disease, and sigmoid colon tumors predicted […]
CT Scans Predict Feasibility of Intestinal Surgery in IBD Patients
Researchers at Cedars-Sinai have developed a groundbreaking technique using preoperative CT scans to predict whether a patient with inflammatory bowel disease (IBD) will be a suitable candidate for ileal pouch-anal anastomosis (IPAA). By measuring critical lengths related to the small bowel’s mesentery, they identified that patients with a mesenteric length of less than 14.6 cm […]
Laparoscopic Sandwich Technique: A Promising Option for Parastomal Hernia Repair
A study from Catalonia, Spain, examined the effectiveness of the laparoscopic sandwich technique for parastomal hernia repair, which uses a double intraperitoneal mesh. Out of 38 patients, the recurrence rate was 7.9%, and the most common complication leading to recurrence was postoperative issues like seroma, hematoma, and surgical site infection. The sandwich technique demonstrated consistent […]
Revolutionizing Colon Surgery: Laser Speckle Imaging Enhances Perfusion Visualization
A game-changing tool has emerged in the world of colon surgery. Laparoscopic laser speckle contrast imaging (LSCI) provides real-time, dye-free visualization of intestinal perfusion. This study, involving 64 patients, revealed LSCI’s potential to accurately image colonic perfusion without disrupting surgery. Operating surgeons found it easy to interpret, and 17% indicated it could change their anastomosis […]
Centralization Key for Small Intestinal Neuroendocrine Tumor Surgery: CentralChirSINET Study
Centralizing surgical care, this study investigated small intestinal neuroendocrine tumor (SI-NET) resections’ outcomes based on procedure volume. High-volume centers (HVCs) performed over five SI-NET resections annually, while low-volume centers (LVCs) did fewer. HVCs showcased better surgical quality, with more lymph nodes resected, advanced techniques, and higher success rates. Optimal SI-NET resection was prevalent in HVCs, […]
Robotic Surgery May Reduce Complications for Minority Patients in Colon Cancer Resection
In a study analyzing over 64,000 patients undergoing elective colon cancer resection, it was found that robotic colectomy led to fewer complications in minority patients compared to laparoscopic colectomy. After adjusting for various factors, there were no significant differences in mortality based on surgical approach or race. However, Black patients who had laparoscopic surgery experienced […]