Findings indicate that non-Hispanic Black patients with colon cancer treated at Commission on Cancer (CoC)-accredited hospitals received significantly more guideline-concordant care than those treated at non-accredited facilities. Specifically, the odds of undergoing necessary lymphadenectomy and chemotherapy were higher (adjusted odds ratios of 1.89 and 2.31, respectively). Moreover, patients at accredited hospitals demonstrated lower cancer-specific mortality, […]

Findings revealed that among Medicare patients undergoing colectomy for colon cancer, those in the highest social vulnerability quintile faced a greater likelihood of unplanned surgeries (35.6% vs. 28.9%) and higher 30-day (3.4% vs. 2.9%) and 1-year mortality rates (10.8% vs. 8.6%). The adjusted odds ratios indicated significant risks associated with higher social vulnerability (AOR 1.36, […]

A study of 3,020 stage III rectal cancer patients identified that 12.4% had a positive circumferential resection margin (CRM). Notably, CRM involvement predominantly occurred through primary tumor invasion (63.2%). Local recurrence and distant metastasis rates varied, being lowest with lymph node metastasis and highest with multiple factors. Multivariate analysis revealed that primary tumor invasion, tumor […]

A nomogram was developed to predict postoperative complications in 207 patients with middle and low rectal cancer undergoing transanal total mesorectal excision (TATME). Findings indicated that 27.5% of patients experienced complications. Key predictors included operation time, smoking history, anastomotic technique, and ASA score, each significantly influencing risk. The model’s accuracy was validated through multiple statistical […]

A systematic review and meta-analysis of six randomized trials, including 1949 patients, demonstrated that indocyanine green (ICG) fluorescence significantly reduces anastomotic leak rates in left-sided colorectal resections. The pooled odds ratio showed a 4.7% absolute reduction in leak rates (OR: 0.586, 95% CI: 0.434-0.792), indicating moderate confidence in its efficacy. ICG may serve as a […]

Oral carbohydrate loading before elective colorectal surgery significantly reduces postoperative insulin resistance, inflammatory markers, and improves patient well-being. In a randomized controlled trial with 72 participants, the carbohydrate loading group showed a marked decrease in insulin resistance on the day of surgery and postoperatively. Additionally, patients experienced less thirst, hunger, and dry mouth, contributing to […]

Among 339 patients with locally advanced rectal cancer, 208 (61.3%) completed total neoadjuvant therapy, achieving a final complete response (CR) rate of 42.3%. Notably, 57 patients (27.4%) sustained clinical CR for over a year, while 42 patients showed pathologic CR post-surgery. Predictors of CR included low rectal tumor location, absence of extramural vascular invasion, and […]

In a multicenter study of 178 patients with mid-low rectal adenocarcinoma, 80.9% maintained rectal preservation after neoadjuvant treatment using either transanal local excision or a watch-and-wait approach. Overall survival at three years was 80.6%, while disease-free survival reached 97.6%. Local recurrence-free and distant recurrence-free survival rates were reported at 90.0% and 94.6%, respectively. Stoma-free survival […]

A multicenter analysis revealed that robot-assisted pelvic exenteration (RPE) significantly reduces blood loss, transfusion rates, and postoperative complications compared to open (OPE) and laparoscopic pelvic exenteration (LPE). Specifically, RPE resulted in blood loss of 408 ml versus 2385 ml for OPE, with a transfusion rate of 32% compared to 82% for OPE. Complication rates over […]