In a study of 2368 patients undergoing minimally invasive colorectal cancer surgery, prolonged postoperative ileus (PPOI) occurred in 9.5% of cases. Six independent risk factors were identified for PPOI: advanced age, male sex, comorbidity index ≥6, preoperative sarcopenia, prognostic nutritional index, and intraoperative fluid overload. A nomogram was developed, achieving area under the curve (AUC) […]

A systematic review and meta-analysis analyzing 94,833 patients revealed that alvimopan significantly lowers the risk of postoperative ileus (odds ratio: 0.57) and shortens hospital stays in individuals undergoing bowel resection. These findings strongly support the routine incorporation of alvimopan into enhanced recovery after surgery programs for open bowel resections. Further investigation is required to explore […]

In patients with stage IIA rectal cancer above the peritoneal reflection who did not receive preoperative chemoradiotherapy, adjuvant chemotherapy (AC) demonstrated significantly improved 5-year overall survival (93.2% vs. 84.6%, p = .001) and recurrence-free survival (81.6% vs. 64.1%, p = .01). Patients with one or more risk factors showed marked benefits from AC compared to […]

The study established and validated task-specific metrics for assessing performance in perineal proctectomy, a complex surgical procedure. In three phases, 23 expert colorectal surgeons reached consensus on the metrics, and a subsequent assessment of 22 participants indicated a strong correlation between global and task-specific scores (rs = 0.86; p 

A cohort study found that minimally invasive left colectomy using total intracorporeal anastomosis (TIA) resulted in fewer intraoperative complications and comparable postoperative morbidity compared to extracorporeal anastomosis (EA). Among 246 patients, TIA demonstrated higher C-reactive protein levels and reduced relevant anastomotic bleeding but similar anastomotic dehiscence rates. These results suggest TIA’s technical feasibility and safety, […]

A randomized trial involving 89 patients undergoing elective anal fistula or hemorrhoid surgery revealed that an enhanced recovery protocol utilizing multimodal analgesia substantially decreased oral opioid consumption in the first postoperative week. Patients in the enhanced recovery group reported median oral morphine milligram equivalent (mme) use of 8 mg versus 79 mg in the standard […]

Transmucosal internal sphincterotomy demonstrates significant advantages in treating fissure in ano compared to traditional methods. The procedure had a median operative time of 7 minutes, yielding a mere 2.5% infection rate and 3% transient incontinence rate. Postoperative pain was notably lower, with a majority of patients healing within 9 weeks and only 1.6% experiencing recurrence. […]

A study involving 604 low rectal cancer patients revealed a 71.9% successful sphincter-preserving resection (SSPR) rate, with hospital rates ranging from 37.7% to 94.4%. Researchers developed seven AI algorithms, including logistic regression and light gradient boosting, achieving excellent discrimination for predicting SSPR, with Area Under the Receiver Operating Characteristic (AUROC) values exceeding 0.8 for the […]

Evaluation of tumor necrosis as a prognostic indicator in colorectal cancer led to the development of criteria for three assessment methods: average percentage, hotspot, and linear methods. All methods demonstrated independent predictive ability for colorectal cancer-specific survival, with the average percentage method showing the highest hazard ratios. Reproducibility assessments revealed strong agreement among investigators, particularly […]