A nomogram incorporating treatment data proved better than the AJCC staging system in predicting overall survival for gastroenteropancreatic neuroendocrine tumors. Key factors include sex, age, race, tumor location, and treatment modalities. Internal and external validation showed superior performance, advocating for individual risk evaluation to enhance patient outcomes and quality of life. Journal Article by Wu […]
Category: Intestine and Lower Gastrointestinal Tract
Low Morbidity and High Survival with Surgical Microwave Ablation for Colorectal Liver Metastasis
Researchers conducted a retrospective review of 394 microwave ablation (MWA) procedures on 328 patients with colorectal liver metastasis. The study found a low morbidity rate, with Clavien-Dindo grade III or IV complications occurring in 3.6% of patients, all of whom had concomitant procedures. Incomplete ablation and local recurrence rates were 1.5% and 6.3% per tumor, […]
Minimally Invasive Surgery Conversion Provides Survival Benefit in Colon Cancer
Conversion from minimally invasive surgery to open surgery in colon cancer patients resulted in higher overall survival compared to upfront laparotomy. This survival advantage was particularly notable in patients over 65 years old, those with significant comorbidities, and individuals with left-sided tumors. Minimally invasive surgery should be favored in the absence of contraindications for patients […]
Primary Anastomosis with Diverting Loop Ileostomy in Acute Complicated Diverticulitis
A study of 16,921 cases of nonelective sigmoidectomy for acute complicated diverticulitis revealed a rising trend in the use of primary anastomosis with diverting loop ileostomy, from 5.3% in 2012 to 8.4% in 2020. Compared to Hartmann’s procedure, primary anastomosis with diverting loop ileostomy was associated with lower rates of major adverse events (24.6% vs […]
Improved Intraoperative ICGFA Guidance for Bowel Transection
A novel patient-calibrated quantitative ICGFA method was developed to recommend optimal bowel transection sites during surgery, showing 85% agreement with baseline perfusion. The software successfully identified expert surgical transection sites in almost all cases, reducing the risk of anastomotic complications. High-resolution augmented reality heatmaps were generated for guidance, integrating seamlessly into existing clinical workflow and […]
Rectal Cancer Guidelines: Inconsistent Reporting Quality Raises Concerns about Transparency and Evidence Use
Clinical practice guidelines for rectal cancer vary in reporting quality, with unique weaknesses in basic information, evidence, recommendations, and review processes. Common themes include limited financial discussion and lack of transparency. Even with variability, current guidelines meet most checklist elements, highlighting the importance of high-quality reporting standards for expert guideline creation. Journal Article by Cai […]
Predictors of Non-operative Treatment Failure in Patients with Acute Diverticulitis and Abscess
The study identified independent predictors of failure in non-operative treatment for patients with diverticular abscesses, highlighting the significant role of Hinchey classification, tobacco smoking, and abscess characteristics. Percutaneous drainage did not impact treatment success in larger abscesses. This underscores the need for targeted interventions in diverticular disease management, particularly for high-risk patient groups. Journal Article […]
Surgeons demonstrate accuracy in predicting radiological sarcopenia in colorectal cancer surgery
Surgeons exhibited high accuracy in identifying radiological sarcopenia in patients with colorectal cancer, with substantial agreement with radiologists. Results showed strong correlations and favorable sensitivity and specificity levels for both junior and senior surgeons, particularly when using a simplistic criterion. The study suggests that the simplistic criterion is preferable over a composite criterion for predicting […]
Healthy Teeth Count as Predictor for Rectal Cancer Chemoradiotherapy Response
Patients with a higher number of healthy teeth had a better response to preoperative chemoradiotherapy (CRT) for rectal cancer, as indicated by higher rates of disease downstaging and complete response. A study of 30 patients showed that those with ≥15 teeth had better outcomes, with a significant difference in disease-free survival rate and a tendency […]
Prognostic Factors and Nomogram Development in Stage III T3-T4 Colon Cancer
Conditional survival analysis for stage III T3-T4 colon cancer identified several risk factors for reduced one-year postoperative conditional survival (COS) and conditional cancer-specific survival (CCSS), including age, PT stage, PN stage, and chemotherapy receipt. This SEER database study of 18,190 patients developed predictive nomograms with a C-index above 0.70, demonstrating reliable and stable performance. The […]