Researchers conducted a prospective observational study to develop a predictive risk model for the recurrence of acute diverticulitis (AD) after the first episode. They analyzed data from 368 patients with AD who had a good response to treatment and found that colonic perforation in the antimesenteric location and a CRP level greater than 100 mg/dL […]
Category: Intestine and Lower Gastrointestinal Tract
ctDNA Assessment in Characterizing Recurrence Sites after Resection for Metastatic Colorectal Cancer
Among 31 patients who underwent optimal resection for metastatic colorectal cancer (mCRC), circulating tumor DNA (ctDNA) was detected in 83.4% of those who experienced postoperative recurrence, while remaining undetectable in those without recurrence. ctDNA was detected earlier than clinical diagnosis by a median of nine weeks, and its levels were significantly lower in peritoneal-only recurrence […]
Liposomal Bupivacaine Enhances Pain Control and Reduces Opioid Use in Hemorrhoidectomy
A systematic review and meta-analysis assessed the efficacy of liposomal bupivacaine (LB) compared to conventional anesthetic or placebo in hemorrhoidectomy patients. The analysis included three randomized clinical trials involving 338 patients. LB demonstrated a significant reduction in pain scores at 72 hours post-surgery compared to conventional anesthetic or placebo. LB also resulted in longer time […]
Comparable Long-Term Survival in Robot-assisted and Laparoscopic Surgery for Colon Cancer
The study aimed to compare long-term survival outcomes in patients undergoing robot-assisted surgery (RAS) or laparoscopic surgery (LAS) for colon cancer. The analysis included 7565 patients, out of which 6905 (91%) underwent LAS and 660 (9%) underwent RAS. The findings revealed that LAS patients had a significantly higher risk of cancer recurrence compared to RAS […]
Racial Disparities in Surgical Treatment Offer for Neuroendocrine Neoplasms
The study investigated the factors associated with offering surgery for pancreatic and small bowel neuroendocrine neoplasms (pannen and sbnen). Analysis of the surveillance databases revealed that non-white race was associated with decreased odds of surgery offer for sbnen but not pannen. These findings highlight racial/ethnic disparities in the course of treatment, indicating that non-white patients […]
Long-term functional disturbances observed in female patients after multivisceral resection for advanced rectal cancers
Female patients who underwent multivisceral resection for rectal cancer experienced long-term functional disturbances, particularly in urinary and sexual functions, according to a cross-sectional study. Out of the 198 patients who had the surgery, 69 were assessed for functional outcomes. The study found that the removal of the uterus and posterior vaginal wall were common procedures, […]
A Comparative Analysis of Surgical Techniques and Outcomes for Internal Hemipelvectomy
Implementing advancements in technology and surgical technique for internal hemipelvectomy procedures can significantly impact patient outcomes. A retrospective study conducted at a single institution examined the experiences of surgeons and the utilization of new techniques and technologies over a 26-year period. The study found that the use of three-dimensional (3D) computer navigation and customized 3D-printed […]
Optimal Follow-up Methods and Intensity after Surgery for Colorectal Liver Metastases
Recurrence after surgery for colorectal liver metastases (CRLM) is common within two years, but there is no established guidance on follow-up methods and intensity. A systematic review of 25 articles involving 9,945 patients revealed wide variation in follow-up methods, with CT as the most common imaging modality and CEA as the most common blood test. […]
Long-Course Chemoradiotherapy Outperforms Short-Course Radiotherapy in Locally Advanced Rectal Cancer
The study compared the oncological outcomes of long-course chemoradiotherapy (LC-CRT) and short-course radiotherapy with delayed surgery (SCRT-delay) in locally advanced rectal cancer (LARC) patients. The results showed that LC-CRT had higher overall survival (OS) rates at 1, 3, and 5 years compared to SCRT-delay. Additionally, LC-CRT group had higher cancer-specific survival (CSS) rates at 1, […]
Laparoscopic Portal Vein Ligation and Embolization Facilitate Safe Second Hepatectomy for Unresectable Colorectal Liver Metastases
Laparoscopic two-stage hepatectomy with portal vein embolization ensures safe completion of surgery for initially unresectable colorectal liver metastases. Three patients received chemotherapy followed by laparoscopic colorectal resection and limited hepatectomies. After right portal vein ligation, laparoscopic portal vein embolization using ethanol facilitated the second hepatectomy. No postoperative complications occurred in six surgeries, suggesting the safety […]