The impact of neoadjuvant radiation therapy on the outcomes of patients with stage II-III mucinous rectal carcinoma was assessed using data from the national cancer database. After propensity-score matching, it was found that patients who received neoadjuvant radiation therapy had marginal downstaging of the disease, fewer examined and positive lymph nodes, and similar overall survival […]
Category: Intestine and Lower Gastrointestinal Tract
International Consensus Achieved on Core Descriptor Sets for Rectal Prolapse Outcomes Research
Experts from around the world have achieved international consensus on core descriptor sets for rectal prolapse outcomes research. Through a three-round Delphi process, experts agreed on minimum descriptors to consider during clinical care, which were then grouped into core descriptor sets. Key findings included the correlation of age, body mass index, frailty, nutrition, and American […]
Which Antibiotic Regimen Fails in Nonoperative Treatment of Diverticulitis and Appendicitis?
Empiric antibiotic treatment of appendicitis is more likely to be associated with the need for additional antibiotics or procedure within 90 days compared to diverticulitis. Cephalosporin + metronidazole (c + m) was the most commonly used antibiotic regimen for appendicitis, while quinolone + metronidazole was more commonly used for diverticulitis. Treatment with c + m […]
Prophylactic Clipping Does Not Prevent Delayed Bleeding After Colorectal Cold Snare Polypectomy in Patients on Antithrombotic Agents
Prophylactic clipping may not be necessary to prevent delayed bleeding after colorectal cold snare polypectomy in patients on antithrombotic agents, according to a retrospective study. The rates of delayed bleeding and hematochezia did not significantly differ between patients with and without prophylactic clipping. These findings suggest that prophylactic clipping may not be effective in preventing […]
Surgery alone may provide similar outcomes to neoadjuvant treatment for T3 rectal cancer.
Neoadjuvant treatment (NCRT) may not be necessary for all patients with T3 rectal cancer. This study compared the outcomes of patients with mid-low rectal cancer treated with either surgery alone or NCRT followed by surgery. After analyzing 1,509 patients, the study found that surgery alone provided similar long-term outcomes to NCRT followed by surgery. While […]
Impact of neoadjuvant therapy on nodal harvest in clinical stage III rectal cancer: Optimum cut-offs for nodal staging
The study investigated the impact of neoadjuvant therapy on nodal harvest in clinical stage III rectal cancer. The current standard of a minimum lymph node harvest (lnh) of 12 for appropriate nodal staging in resectable rectal cancer was challenged as neoadjuvant therapy led to a decrease in the number of lnh. The results showed that […]
A Precise Robotic Technique Enhances Outcomes and Reduces Costs for Low Anterior Resection
Researchers present a novel robotic-assisted approach for intracorporeal rectal transection and hand-sewn anastomosis in low anterior resection. This technique addresses limitations of conventional methods by utilizing the advantages of the robotic platform, ensuring standardized exposure during rectal transection, and recognizing the significance of avoiding staple-related complications. The innovation holds promise to significantly improve patient outcomes […]
Study Finds Significant Variation in Hospital Performance After Colorectal Cancer Surgery
Significant variations in hospital performance after colorectal cancer surgery were observed in a Dutch population-based study. The study analyzed data from over 44,000 colorectal cancer patients and found that two hospitals performed worse than expected in terms of 90-day mortality, while significant outliers were observed for anastomotic leakage in both colon cancer and rectal cancer […]
Prophylactic Hyperthermic Intraperitoneal Chemotherapy Improves Prognosis in CT4N0-1M0 Colorectal Cancer
A propensity score matching study analyzed 220 colorectal cancer patients undergoing treatment in China. Prophylactic hyperthermic intraperitoneal chemotherapy (HIPEC) was associated with improved 3-year disease-free survival (DFS) compared to no HIPEC (HR 0.43). However, this benefit was not observed in patients with CT4N2M0 cancer. Laparoscopic surgery followed by HIPEC did not increase the risk of […]
Improved Predictive Value: GLIM Criteria and HGS Test in Overweight Colorectal Cancer Patients
The retrospective study, which enrolled 850 overweight colorectal cancer patients, found that the incidence of malnutrition was 12.4% in the GLIM group and 6.4% in the HGS-GLIM group. Both malnutrition groups had a significantly higher incidence of complications compared to the control group. Patients in the HGS-GLIM-malnutrition group had worse overall survival and disease-free survival. […]