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Among elderly colorectal cancer patients, right-sided colon cancers (RCCs) demonstrated better long-term outcomes compared to left-sided colorectal cancers (LCCs). RCCs were more prevalent in female patients with renal comorbidities and a history of abdominal surgery. They were larger, invaded more deeply, and had unique histological…
Higher carcinoembryonic antigen levels, recurrence, and lack of surgery are linked to poor survival in colorectal cancer patients in Karachi, Pakistan. Monitoring CEA levels, timely surgical interventions, and follow-up care for recurrent cases can enhance survival outcomes. Early-onset colorectal cancer cases (
Feasibility and efficacy of robotic complete mesocolic excision (CME) with intracorporeal anastomosis for right colon cancer were analyzed in 110 patients. Results show a median operative time of 184 minutes, minimal blood loss, and low complication rates. Conversions were minimal, with acceptable postoperative outcomes. Robotic…
3D laparoscopy demonstrates significant improvement in intraoperative blood loss, faster postoperative recovery, shorter operation time, and hospital stay compared to conventional 2D laparoscopy for radical rectal cancer surgery. However, no clear advantage was observed for radical colon cancer surgery. Additionally, 3D laparoscopy increases the number…
Long-course chemoradiotherapy with consolidation chemotherapy, short-course radiotherapy with consolidation chemotherapy, and induction chemotherapy with long-course chemoradiotherapy outperform standard treatment for locally advanced rectal cancer, improving pathological complete response rates. These findings support their recognition as first-line treatments, offering good tolerability and optimal postoperative outcomes.
Deciphering heterogeneous tertiary lymphoid structures (TLS) patterns in colorectal cancer revealed three clusters with different prognostic implications. High metabolic activity and stromal pathways linked to worse outcomes, while immune activation pathways indicated improved prognosis and better response to immunotherapy. A new TLScore based on 9…
Dependent functional status significantly increases the risks of mortality, pulmonary complications, sepsis, extended postoperative NPO/NGT use, non-home discharge, 30-day readmission, and longer hospital stays post-colectomy for volvulus. Identifying DFS as an independent risk factor emphasizes its impact on postoperative outcomes, enabling tailored preoperative assessments and…
A noticeable decline in rates of superficial and deep incisional infections has been observed from 2013 to 2020 in colorectal surgery, attributed to increased use of minimally invasive techniques. However, organ space infections have shown an upward trend during the same period. Adoption of minimally…
International expert consensus on operative descriptors for rectal prolapse surgery was achieved through a Delphi process. A synoptic operative report was developed, including 16 key descriptors with over 70% consensus. This standardized reporting aims to enhance clinical communication, quality measures, and research in pelvic floor…
Male patients with small intestinal stromal tumors (SISTs) have a higher risk of mortality compared to females. Females exhibit superior overall survival and cancer-specific survival rates than males. Surgical intervention significantly improves survival outcomes in both genders. Gender, along with age, grade, TNM stage, surgery,…
