Aprepitant significantly reduces postoperative nausea and vomiting in patients undergoing metabolic bariatric surgery, improving recovery and patient satisfaction. Meta-analysis of six studies involving 929 patients showed a significant decrease in ponv incidence with aprepitant, particularly at 0, 6, and 12 hours postoperatively. Administering aprepitant within the first 24 hours post-surgery is recommended for optimal efficacy. […]

Early body-weight loss (< 37.7% EBWL) at 3 months post-laparoscopic sleeve gastrectomy predicts poorer long-term weight loss outcomes. High BMI, elevated neutrophil-to-lymphocyte ratio (≥ 2.36), and female sex are significant risk factors for suboptimal weight loss. These findings highlight the potential utility of targeted interventions such as adjuvant weight loss medications in at-risk patients. Journal […]

Conversion from Sleeve Gastrectomy to Roux-en-Y Gastric Bypass significantly reduced GERD symptoms and PPI use, with 70% of patients experiencing complete symptom resolution and 60% discontinuing PPIs. This approach led to improved postoperative outcomes, decreasing daily symptoms of GERD and the need for PPIs. The study highlights the effectiveness of Roux-en-Y Gastric Bypass for managing […]

Study reveals a non-linear, inverted U-shaped association between preoperative BMI and optimal weight loss outcomes post bariatric surgery. Setting a BMI threshold of 42.9 is critical in predicting optimal clinical responses in patients with obesity. Quartile odds ratios and restricted cubic spline analysis support this correlation, highlighting the importance of personalized treatment strategies based on […]

One-anastomosis gastric bypass (OAGB) and Roux-en-Y gastric bypass (RYGB) showed similar improvements in renal function one year post-surgery, with OAGB leading to greater weight loss. Both procedures resulted in significantly higher estimated glomerular filtration rates. Younger age and lower baseline renal function were associated with better postoperative outcomes. OAGB could be a viable option for […]

Bariatric intervention significantly reduced BMI and intrahepatic fat in patients with obesity, leading to improvements in histologic features of metabolic dysfunction-associated steatohepatitis. Nonalcoholic fatty liver disease activity score decreased significantly at various time points post-intervention. These findings suggest that bariatric intervention may be an effective alternative for obese patients with metabolic dysfunction-associated steatohepatitis unresponsive to […]

Analysis of revisional and conversional sleeve gastrectomy procedures with concurrent hiatal hernia repair showed increased operative time, risk of postoperative pneumonia, and readmission within thirty days for patients with hiatal hernia repair. Despite these findings, patients undergoing laparoscopic revisional or conversional sleeve gastrectomy with hiatal hernia repair did not experience higher risks of death, postoperative […]

Individuals with lower polygenic risk scores experienced better weight loss outcomes after bariatric surgery compared to those with higher scores, especially in patients undergoing roux-en-y gastric bypass. Genetic background, assessed through polygenic risk scores, plays a significant role in long-term weight loss post-surgery, alongside factors like sex, age, and initial BMI. These findings suggest the […]

Significant weight loss and remission of type 2 diabetes mellitus were observed in patients post-sleeve gastrectomy. Patients exhibited low citrulline and high I-FABP levels preoperatively, which normalized postoperatively. The study found a positive correlation between the I-FABP/citrulline ratio and weight, BMI, glucose, insulin, and c-peptide levels. Sleeve gastrectomy not only improves enteroendocrine function but also […]

Male patients had slightly greater weight loss and higher complication rates compared to females following bariatric surgery. However, these differences were not clinically significant. Providers should consider referring males earlier for surgery given their higher comorbidity rates. This study highlights the need to assess sex differences in outcomes to personalize bariatric care effectively. Journal Article […]